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Tumor Tissue Gene Panel With MSI And TMB

Florida rates for HCPCS 0334U

Guides treatment choice in solid tumors by identifying the genetic changes driving the cancer. Preserved, formalin-fixed tumor tissue is sequenced across at least eighty-four genes. The service also reports microsatellite instability and tumor mutational burden — two whole-tumor measures counted outside that gene total, which help predict response to immunotherapy.

Rates data updated July 2026.

How much does Tumor Tissue Gene Panel With MSI And TMB cost?

$2,089

Typical negotiated rate. In Florida, July 2026.

Insurers have agreed to pay about $2,089 for this service. The price depends on where it is billed: about $2,089 from a physician practice, and about $6,457 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,089$1,738 to $2,399
FacilityA hospital or hospital-owned outpatient department$6,457$2,951 to $10,471

How much rates vary

Facilitymedian $6,457 · 10th to 90th $2,089 to $19,055Professionalmedian $2,089 · 10th to 90th $1,549 to $2,754
$200$500$1K$2K$5K$10K$20Kfacility $6,457professional $2,089

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,089.30
Median
$8,317.64
Typical High
$19,054.61
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$2,089.30
Typical High
$2,511.89
AvMed
Setting
Professional
Modifier
Global
Typical Low
$2,818.38
Median
$3,467.37
Typical High
$3,467.37
Cigna
Setting
Facility
Modifier
Global
Typical Low
$4,570.88
Median
$7,244.36
Typical High
$14,125.38
Cigna
Setting
Professional
Modifier
Global
Typical Low
$4,265.80
Median
$5,128.61
Typical High
$16,982.44
Florida Blue
Setting
Facility
Modifier
Global
Typical Low
$6,456.54
Median
$6,456.54
Typical High
$6,456.54
Florida Blue
Setting
Professional
Modifier
Global
Typical Low
$2,089.30
Median
$2,089.30
Typical High
$2,570.40
Molina
Setting
Professional
Modifier
Global
Typical Low
$50.12
Median
$2,089.30
Typical High
$3,467.37
United
Setting
Facility
Modifier
Global
Typical Low
$1,230.27
Median
$2,630.27
Typical High
$3,630.78
United
Setting
Professional
Modifier
Global
Typical Low
$1,023.29
Median
$1,230.27
Typical High
$3,890.45
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$2,089.30
Median
$2,089.30
Typical High
$3,467.37

Where Florida sits

The same service costs 6.5 times more in Alaska than in Montana. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Florida· 46th of 51

$2,089

AK $7,943MT $1,230

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.