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Tumor Tissue Gene Panel With MSI And TMB

Colorado rates for HCPCS 0334U

Guides treatment choice in solid tumors by identifying the genetic changes driving the cancer. Preserved, formalin-fixed tumor tissue is sequenced across at least eighty-four genes. The service also reports microsatellite instability and tumor mutational burden — two whole-tumor measures counted outside that gene total, which help predict response to immunotherapy.

Rates data updated July 2026.

How much does Tumor Tissue Gene Panel With MSI And TMB cost?

$6,310

Typical negotiated rate. In Colorado, July 2026.

Insurers have agreed to pay about $6,310 for this service. The price depends on where it is billed: about $1,738 from a physician practice, and about $9,333 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$1,738$1,230 to $2,754
FacilityA hospital or hospital-owned outpatient department$9,333$5,888 to $14,791

How much rates vary

Facilitymedian $9,333 · 10th to 90th $3,548 to $17,783Professionalmedian $1,738 · 10th to 90th $1,230 to $3,090
$1K$2K$5K$10K$20Kfacility $9,333professional $1,738

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$3,630.78
Median
$12,302.69
Typical High
$19,498.45
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$2,344.23
Typical High
$3,090.30
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$4,466.84
Median
$10,000.00
Typical High
$17,782.79
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,174.90
Median
$1,230.27
Typical High
$2,951.21
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,862.09
Median
$2,290.87
Typical High
$10,715.19
Cigna
Setting
Professional
Modifier
Global
Typical Low
$4,265.80
Median
$4,265.80
Typical High
$5,128.61
Denver HMP
Setting
Facility
Modifier
Global
Typical Low
$2,630.27
Median
$3,467.37
Typical High
$4,897.79
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$4,897.79
Median
$4,897.79
Typical High
$5,011.87
Select Health
Setting
Facility
Modifier
Global
Typical Low
$3,715.35
Median
$6,456.54
Typical High
$7,413.10
Select Health
Setting
Professional
Modifier
Global
Typical Low
$2,454.71
Median
$3,467.37
Typical High
$5,248.07
United
Setting
Facility
Modifier
Global
Typical Low
$2,951.21
Median
$3,162.28
Typical High
$4,365.16
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,230.27
Typical High
$2,137.96

Where Colorado sits

The same service costs 6.5 times more in Alaska than in Montana. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 2nd of 51

$6,310

AK $7,943MT $1,230

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.