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Liver Cancer Screening Blood Test

South Dakota rates for HCPCS 0333U

Screens people at raised risk for hepatocellular carcinoma, the most common primary liver cancer, so that a tumor can be caught early. It combines methylation patterns on cell-free DNA circulating in the blood with three established liver tumor markers, AFP, AFP-L3 and DCP, and reports a classification.

Rates data updated July 2026.

How much does Liver Cancer Screening Blood Test cost?

$1,202

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $1,202 for this service. Most negotiated rates run $617 to $1,585.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $759 · 10th to 90th $468 to $1,047Professionalmedian $1,259 · 10th to 90th $513 to $1,738
$500$1Kfacility $759professional $1,259

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$467.74
Median
$758.58
Typical High
$758.58
Aetna
Setting
Professional
Modifier
Global
Typical Low
$512.86
Median
$616.60
Typical High
$616.60
Cigna
Setting
Professional
Modifier
Global
Typical Low
$954.99
Median
$1,258.93
Typical High
$1,584.89
Medica
Setting
Facility
Modifier
Global
Typical Low
$630.96
Median
$630.96
Typical High
$1,202.26
Medica
Setting
Professional
Modifier
Global
Typical Low
$338.84
Median
$338.84
Typical High
$3,311.31
Midlands
Setting
Professional
Modifier
Global
Typical Low
$794.33
Median
$794.33
Typical High
$794.33
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$1,122.02
Median
$1,584.89
Typical High
$1,819.70
United
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$398.11
Typical High
$870.96
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$660.69
Median
$660.69
Typical High
$660.69

Where South Dakota sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 3rd of 51

$1,202

AK $1,479WY $398

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.