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Liver Cancer Screening Blood Test

South Carolina rates for HCPCS 0333U

Screens people at raised risk for hepatocellular carcinoma, the most common primary liver cancer, so that a tumor can be caught early. It combines methylation patterns on cell-free DNA circulating in the blood with three established liver tumor markers, AFP, AFP-L3 and DCP, and reports a classification.

Rates data updated July 2026.

How much does Liver Cancer Screening Blood Test cost?

$525

Typical negotiated rate. In South Carolina, July 2026.

Insurers have agreed to pay about $525 for this service. The price depends on where it is billed: about $513 from a physician practice, and about $1,349 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$513$513 to $525
FacilityA hospital or hospital-owned outpatient department$1,349$513 to $2,138

How much rates vary

Facilitymedian $1,349 · 10th to 90th $490 to $3,162Professionalmedian $513 · 10th to 90th $398 to $575
$50$100$200$500$1K$2Kfacility $1,349professional $513

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$512.86
Median
$1,621.81
Typical High
$3,162.28
Aetna
Setting
Professional
Modifier
Global
Typical Low
$512.86
Median
$512.86
Typical High
$537.03
BCBS
Setting
Professional
Modifier
Global
Typical Low
$660.69
Median
$707.95
Typical High
$1,000.00
Cigna
Setting
Facility
Modifier
Global
Typical Low
$446.68
Median
$1,698.24
Typical High
$3,801.89
Medcost
Setting
Facility
Modifier
Global
Typical Low
$436.52
Median
$549.54
Typical High
$870.96
Molina
Setting
Professional
Modifier
Global
Typical Low
$30.20
Median
$30.20
Typical High
$30.20
United
Setting
Facility
Modifier
Global
Typical Low
$602.56
Median
$660.69
Typical High
$660.69
United
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$398.11
Typical High
$660.69

Where South Carolina sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 41st of 51

$525

AK $1,479WY $398

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.