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Liver Cancer Screening Blood Test

North Carolina rates for HCPCS 0333U

Screens people at raised risk for hepatocellular carcinoma, the most common primary liver cancer, so that a tumor can be caught early. It combines methylation patterns on cell-free DNA circulating in the blood with three established liver tumor markers, AFP, AFP-L3 and DCP, and reports a classification.

Rates data updated July 2026.

How much does Liver Cancer Screening Blood Test cost?

$525

Typical negotiated rate. In North Carolina, July 2026.

Insurers have agreed to pay about $525 for this service. The price depends on where it is billed: about $525 from a physician practice, and about $575 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$525$525 to $661
FacilityA hospital or hospital-owned outpatient department$575$525 to $794

How much rates vary

Facilitymedian $575 · 10th to 90th $525 to $1,445Professionalmedian $525 · 10th to 90th $437 to $1,072
$500$1K$2Kfacility $575professional $525

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$524.81
Median
$524.81
Typical High
$1,445.44
Aetna
Setting
Professional
Modifier
Global
Typical Low
$436.52
Median
$524.81
Typical High
$524.81
BCBS
Setting
Facility
Modifier
Global
Typical Low
$1,479.11
Median
$1,479.11
Typical High
$2,089.30
BCBS
Setting
Professional
Modifier
Global
Typical Low
$562.34
Median
$660.69
Typical High
$1,202.26
Cigna
Setting
Facility
Modifier
Global
Typical Low
$549.54
Median
$1,445.44
Typical High
$3,019.95
Medcost
Setting
Facility
Modifier
Global
Typical Low
$501.19
Median
$588.84
Typical High
$812.83
Medcost
Setting
Professional
Modifier
Global
Typical Low
$426.58
Median
$426.58
Typical High
$426.58
United
Setting
Facility
Modifier
Global
Typical Low
$398.11
Median
$776.25
Typical High
$812.83
United
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$398.11
Typical High
$707.95
Wellcare
Setting
Facility
Modifier
Global
Typical Low
$3,162.28
Median
$3,162.28
Typical High
$3,162.28
Wellcare
Setting
Professional
Modifier
Global
Typical Low
$3,311.31
Median
$3,311.31
Typical High
$5,011.87

Where North Carolina sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 39th of 51

$525

AK $1,479WY $398

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.