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Liver Cancer Screening Blood Test

Missouri rates for HCPCS 0333U

Screens people at raised risk for hepatocellular carcinoma, the most common primary liver cancer, so that a tumor can be caught early. It combines methylation patterns on cell-free DNA circulating in the blood with three established liver tumor markers, AFP, AFP-L3 and DCP, and reports a classification.

Rates data updated July 2026.

How much does Liver Cancer Screening Blood Test cost?

$759

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $759 for this service. The price depends on where it is billed: about $708 from a physician practice, and about $1,047 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$708$575 to $1,995
FacilityA hospital or hospital-owned outpatient department$1,047$646 to $1,148

How much rates vary

Facilitymedian $1,047 · 10th to 90th $562 to $1,288Professionalmedian $708 · 10th to 90th $398 to $1,995
$500$1K$2Kfacility $1,047professional $708

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$645.65
Median
$1,122.02
Typical High
$1,288.25
Aetna
Setting
Professional
Modifier
Global
Typical Low
$562.34
Median
$575.44
Typical High
$1,122.02
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$707.95
Median
$1,995.26
Typical High
$1,995.26
Cigna
Setting
Facility
Modifier
Global
Typical Low
$933.25
Median
$1,380.38
Typical High
$3,388.44
Medica
Setting
Facility
Modifier
Global
Typical Low
$562.34
Median
$794.33
Typical High
$3,162.28
Medica
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$398.11
Typical High
$3,311.31
United
Setting
Facility
Modifier
Global
Typical Low
$239.88
Median
$660.69
Typical High
$794.33
United
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$398.11
Typical High
$776.25

Where Missouri sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 13th of 51

$759

AK $1,479WY $398

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.