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Liver Cancer Screening Blood Test

Massachusetts rates for HCPCS 0333U

Screens people at raised risk for hepatocellular carcinoma, the most common primary liver cancer, so that a tumor can be caught early. It combines methylation patterns on cell-free DNA circulating in the blood with three established liver tumor markers, AFP, AFP-L3 and DCP, and reports a classification.

Rates data updated July 2026.

How much does Liver Cancer Screening Blood Test cost?

$661

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $661 for this service. The price depends on where it is billed: about $661 from a physician practice, and about $1,514 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$661$501 to $661
FacilityA hospital or hospital-owned outpatient department$1,514$912 to $1,950

How much rates vary

Facilitymedian $1,514 · 10th to 90th $468 to $2,291Professionalmedian $661 · 10th to 90th $398 to $1,072
$500$1K$2K$5Kfacility $1,514professional $661

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$467.74
Median
$1,479.11
Typical High
$2,137.96
Aetna
Setting
Professional
Modifier
Global
Typical Low
$363.08
Median
$467.74
Typical High
$537.03
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$724.44
Median
$1,778.28
Typical High
$3,162.28
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$398.11
Median
$660.69
Typical High
$2,511.89
Cigna
Setting
Facility
Modifier
Global
Typical Low
$446.68
Median
$501.19
Typical High
$1,071.52
Cigna
Setting
Professional
Modifier
Global
Typical Low
$812.83
Median
$977.24
Typical High
$2,398.83
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$4,897.79
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$954.99
Median
$954.99
Typical High
$1,122.02
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$660.69
Median
$660.69
Typical High
$1,071.52
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$724.44
Median
$1,778.28
Typical High
$3,162.28
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$398.11
Median
$660.69
Typical High
$2,511.89
United
Setting
Facility
Modifier
Global
Typical Low
$398.11
Median
$602.56
Typical High
$794.33
United
Setting
Professional
Modifier
Global
Typical Low
$398.11
Median
$660.69
Typical High
$1,148.15

Where Massachusetts sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 21st of 51

$661

AK $1,479WY $398

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.