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Liver Cancer Screening Blood Test

Illinois rates for HCPCS 0333U

Screens people at raised risk for hepatocellular carcinoma, the most common primary liver cancer, so that a tumor can be caught early. It combines methylation patterns on cell-free DNA circulating in the blood with three established liver tumor markers, AFP, AFP-L3 and DCP, and reports a classification.

Rates data updated July 2026.

How much does Liver Cancer Screening Blood Test cost?

$575

Typical negotiated rate. In Illinois, July 2026.

Insurers have agreed to pay about $575 for this service. The price depends on where it is billed: about $537 from a physician practice, and about $1,047 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$537$490 to $617
FacilityA hospital or hospital-owned outpatient department$1,047$676 to $1,349

How much rates vary

Facilitymedian $1,047 · 10th to 90th $537 to $1,445Professionalmedian $537 · 10th to 90th $363 to $1,148
$200$500$1K$2Kfacility $1,047professional $537

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$537.03
Median
$1,047.13
Typical High
$1,412.54
Aetna
Setting
Professional
Modifier
Global
Typical Low
$407.38
Median
$537.03
Typical High
$1,348.96
BCBS
Setting
Facility
Modifier
Global
Typical Low
$794.33
Median
$891.25
Typical High
$1,071.52
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,230.27
Median
$1,445.44
Typical High
$3,019.95
Cigna
Setting
Professional
Modifier
Global
Typical Low
$776.25
Median
$812.83
Typical High
$977.24
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$346.74
Median
$891.25
Typical High
$1,202.26
Hally Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$870.96
Median
$870.96
Typical High
$870.96
Molina
Setting
Professional
Modifier
Global
Typical Low
$30.20
Median
$30.20
Typical High
$30.20
United
Setting
Facility
Modifier
Global
Typical Low
$331.13
Median
$794.33
Typical High
$1,318.26
United
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$398.11
Typical High
$660.69

Where Illinois sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 29th of 51

$575

AK $1,479WY $398

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.