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Liver Cancer Screening Blood Test

Florida rates for HCPCS 0333U

Screens people at raised risk for hepatocellular carcinoma, the most common primary liver cancer, so that a tumor can be caught early. It combines methylation patterns on cell-free DNA circulating in the blood with three established liver tumor markers, AFP, AFP-L3 and DCP, and reports a classification.

Rates data updated July 2026.

How much does Liver Cancer Screening Blood Test cost?

$479

Typical negotiated rate. In Florida, July 2026.

Insurers have agreed to pay about $479 for this service. The price depends on where it is billed: about $468 from a physician practice, and about $1,230 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$468$398 to $537
FacilityA hospital or hospital-owned outpatient department$1,230$603 to $1,905

How much rates vary

Facilitymedian $1,230 · 10th to 90th $479 to $3,548Professionalmedian $468 · 10th to 90th $355 to $603
$200$500$1K$2Kfacility $1,230professional $468

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$478.63
Median
$1,584.89
Typical High
$3,548.13
Aetna
Setting
Professional
Modifier
Global
Typical Low
$398.11
Median
$467.74
Typical High
$602.56
AvMed
Setting
Professional
Modifier
Global
Typical Low
$524.81
Median
$660.69
Typical High
$660.69
Cigna
Setting
Facility
Modifier
Global
Typical Low
$338.84
Median
$501.19
Typical High
$2,691.53
Cigna
Setting
Professional
Modifier
Global
Typical Low
$812.83
Median
$977.24
Typical High
$3,162.28
Florida Blue
Setting
Facility
Modifier
Global
Typical Low
$1,230.27
Median
$1,230.27
Typical High
$1,230.27
Florida Blue
Setting
Professional
Modifier
Global
Typical Low
$398.11
Median
$398.11
Typical High
$562.34
Molina
Setting
Professional
Modifier
Global
Typical Low
$50.12
Median
$398.11
Typical High
$660.69
United
Setting
Facility
Modifier
Global
Typical Low
$275.42
Median
$602.56
Typical High
$851.14
United
Setting
Professional
Modifier
Global
Typical Low
$234.42
Median
$281.84
Typical High
$870.96
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$398.11
Median
$398.11
Typical High
$660.69

Where Florida sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Florida· 47th of 51

$479

AK $1,479WY $398

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.