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Liver Cancer Screening Blood Test

Colorado rates for HCPCS 0333U

Screens people at raised risk for hepatocellular carcinoma, the most common primary liver cancer, so that a tumor can be caught early. It combines methylation patterns on cell-free DNA circulating in the blood with three established liver tumor markers, AFP, AFP-L3 and DCP, and reports a classification.

Rates data updated July 2026.

How much does Liver Cancer Screening Blood Test cost?

$1,230

Typical negotiated rate. In Colorado, July 2026.

Insurers have agreed to pay about $1,230 for this service. The price depends on where it is billed: about $501 from a physician practice, and about $1,820 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$501$447 to $955
FacilityA hospital or hospital-owned outpatient department$1,820$1,096 to $2,818

How much rates vary

Facilitymedian $1,820 · 10th to 90th $661 to $3,311Professionalmedian $501 · 10th to 90th $275 to $2,089
$500$1K$2K$5Kfacility $1,820professional $501

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$660.69
Median
$2,290.87
Typical High
$3,090.30
Aetna
Setting
Professional
Modifier
Global
Typical Low
$398.11
Median
$501.19
Typical High
$616.60
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$851.14
Median
$1,995.26
Typical High
$3,311.31
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,995.26
Median
$2,089.30
Typical High
$5,011.87
Cigna
Setting
Facility
Modifier
Global
Typical Low
$354.81
Median
$426.58
Typical High
$2,041.74
Cigna
Setting
Professional
Modifier
Global
Typical Low
$812.83
Median
$954.99
Typical High
$977.24
Denver HMP
Setting
Facility
Modifier
Global
Typical Low
$501.19
Median
$660.69
Typical High
$954.99
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$933.25
Median
$933.25
Typical High
$933.25
Select Health
Setting
Facility
Modifier
Global
Typical Low
$691.83
Median
$1,230.27
Typical High
$1,380.38
Select Health
Setting
Professional
Modifier
Global
Typical Low
$467.74
Median
$660.69
Typical High
$1,000.00
United
Setting
Facility
Modifier
Global
Typical Low
$602.56
Median
$691.83
Typical High
$1,000.00
United
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$275.42
Typical High
$489.78

Where Colorado sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 2nd of 51

$1,230

AK $1,479WY $398

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.