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Prenatal Blood Screen For Three Trisomies

South Carolina rates for HCPCS 0327U

Screens a pregnancy for three chromosome conditions: trisomy 21 (Down syndrome), trisomy 18 and trisomy 13. A blood sample from the pregnant person is used, because it carries small amounts of DNA from the placenta, and the result is a risk estimate for each condition. Reporting of fetal sex is an optional addition.

Rates data updated July 2026.

How much does Prenatal Blood Screen For Three Trisomies cost?

$631

Typical negotiated rate. In South Carolina, July 2026.

Insurers have agreed to pay about $631 for this service. The price depends on where it is billed: about $617 from a physician practice, and about $1,950 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$617$617 to $631
FacilityA hospital or hospital-owned outpatient department$1,950$617 to $2,570

How much rates vary

Facilitymedian $1,950 · 10th to 90th $617 to $3,802Professionalmedian $617 · 10th to 90th $479 to $692
$500$1K$2K$5Kfacility $1,950professional $617

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$616.60
Median
$1,949.84
Typical High
$3,801.89
Aetna
Setting
Professional
Modifier
Global
Typical Low
$616.60
Median
$616.60
Typical High
$645.65
BCBS
Setting
Professional
Modifier
Global
Typical Low
$794.33
Median
$851.14
Typical High
$1,621.81
Cigna
Setting
Facility
Modifier
Global
Typical Low
$549.54
Median
$1,995.26
Typical High
$4,570.88
Medcost
Setting
Facility
Modifier
Global
Typical Low
$478.63
Median
$676.08
Typical High
$1,023.29
United
Setting
Facility
Modifier
Global
Typical Low
$707.95
Median
$794.33
Typical High
$794.33
United
Setting
Professional
Modifier
Global
Typical Low
$331.13
Median
$478.63
Typical High
$794.33

Where South Carolina sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 37th of 51

$631

AK $1,778WY $479

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.