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Prenatal Blood Screen For Three Trisomies

Pennsylvania rates for HCPCS 0327U

Screens a pregnancy for three chromosome conditions: trisomy 21 (Down syndrome), trisomy 18 and trisomy 13. A blood sample from the pregnant person is used, because it carries small amounts of DNA from the placenta, and the result is a risk estimate for each condition. Reporting of fetal sex is an optional addition.

Rates data updated July 2026.

How much does Prenatal Blood Screen For Three Trisomies cost?

$676

Typical negotiated rate. In Pennsylvania, July 2026.

Insurers have agreed to pay about $676 for this service. The price depends on where it is billed: about $646 from a physician practice, and about $1,549 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$646$479 to $676
FacilityA hospital or hospital-owned outpatient department$1,549$1,023 to $2,042

How much rates vary

Facilitymedian $1,549 · 10th to 90th $676 to $2,818Professionalmedian $646 · 10th to 90th $437 to $794
$500$1K$2K$5Kfacility $1,549professional $646

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$676.08
Median
$1,548.82
Typical High
$2,818.38
Aetna
Setting
Professional
Modifier
Global
Typical Low
$436.52
Median
$645.65
Typical High
$741.31
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$616.60
Median
$616.60
Typical High
$616.60
Cigna
Setting
Facility
Modifier
Global
Typical Low
$575.44
Median
$1,096.48
Typical High
$2,691.53
Cigna
Setting
Professional
Modifier
Global
Typical Low
$3,801.89
Median
$3,801.89
Typical High
$3,801.89
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$1,047.13
Median
$1,047.13
Typical High
$1,148.15
Geisinger
Setting
Facility
Modifier
Global
Typical Low
$794.33
Median
$794.33
Typical High
$794.33
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$602.56
Median
$912.01
Typical High
$1,513.56
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$933.25
Median
$1,659.59
Typical High
$2,818.38
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$436.52
Median
$645.65
Typical High
$2,344.23
United
Setting
Facility
Modifier
Global
Typical Low
$478.63
Median
$478.63
Typical High
$478.63
United
Setting
Professional
Modifier
Global
Typical Low
$331.13
Median
$478.63
Typical High
$1,071.52

Where Pennsylvania sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Pennsylvania· 27th of 51

$676

AK $1,778WY $479

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.