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Prenatal Blood Screen For Three Trisomies

Missouri rates for HCPCS 0327U

Screens a pregnancy for three chromosome conditions: trisomy 21 (Down syndrome), trisomy 18 and trisomy 13. A blood sample from the pregnant person is used, because it carries small amounts of DNA from the placenta, and the result is a risk estimate for each condition. Reporting of fetal sex is an optional addition.

Rates data updated July 2026.

How much does Prenatal Blood Screen For Three Trisomies cost?

$776

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $776 for this service. The price depends on where it is billed: about $676 from a physician practice, and about $1,259 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$676$501 to $891
FacilityA hospital or hospital-owned outpatient department$1,259$776 to $1,380

How much rates vary

Facilitymedian $1,259 · 10th to 90th $676 to $1,549Professionalmedian $676 · 10th to 90th $479 to $1,380
$500$1K$2Kfacility $1,259professional $676

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$776.25
Median
$1,348.96
Typical High
$1,548.82
Aetna
Setting
Professional
Modifier
Global
Typical Low
$676.08
Median
$691.83
Typical High
$1,621.81
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$489.78
Median
$501.19
Typical High
$1,258.93
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,122.02
Median
$1,659.59
Typical High
$4,073.80
Medica
Setting
Facility
Modifier
Global
Typical Low
$676.08
Median
$954.99
Typical High
$3,801.89
Medica
Setting
Professional
Modifier
Global
Typical Low
$331.13
Median
$478.63
Typical High
$3,981.07
United
Setting
Facility
Modifier
Global
Typical Low
$288.40
Median
$794.33
Typical High
$954.99
United
Setting
Professional
Modifier
Global
Typical Low
$331.13
Median
$478.63
Typical High
$933.25

Where Missouri sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 19th of 51

$776

AK $1,778WY $479

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.