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Prenatal Blood Screen For Three Trisomies

Massachusetts rates for HCPCS 0327U

Screens a pregnancy for three chromosome conditions: trisomy 21 (Down syndrome), trisomy 18 and trisomy 13. A blood sample from the pregnant person is used, because it carries small amounts of DNA from the placenta, and the result is a risk estimate for each condition. Reporting of fetal sex is an optional addition.

Rates data updated July 2026.

How much does Prenatal Blood Screen For Three Trisomies cost?

$794

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $794 for this service. The price depends on where it is billed: about $794 from a physician practice, and about $1,622 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$794$603 to $794
FacilityA hospital or hospital-owned outpatient department$1,622$1,288 to $2,291

How much rates vary

Facilitymedian $1,622 · 10th to 90th $794 to $2,570Professionalmedian $794 · 10th to 90th $479 to $1,318
$500$1K$2K$5Kfacility $1,622professional $794

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$562.34
Median
$1,778.28
Typical High
$2,570.40
Aetna
Setting
Professional
Modifier
Global
Typical Low
$436.52
Median
$562.34
Typical High
$645.65
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$3,801.89
Median
$3,801.89
Typical High
$3,801.89
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$478.63
Median
$478.63
Typical High
$3,981.07
BCBS
Setting
Facility
Modifier
Global
Typical Low
$1,288.25
Median
$1,621.81
Typical High
$2,290.87
Cigna
Setting
Facility
Modifier
Global
Typical Low
$537.03
Median
$616.60
Typical High
$1,288.25
Cigna
Setting
Professional
Modifier
Global
Typical Low
$977.24
Median
$977.24
Typical High
$1,202.26
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$4,897.79
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$1,148.15
Median
$1,148.15
Typical High
$1,348.96
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$794.33
Median
$794.33
Typical High
$1,318.26
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$3,801.89
Median
$3,801.89
Typical High
$3,801.89
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$478.63
Median
$478.63
Typical High
$3,981.07
United
Setting
Facility
Modifier
Global
Typical Low
$478.63
Median
$707.95
Typical High
$954.99
United
Setting
Professional
Modifier
Global
Typical Low
$478.63
Median
$794.33
Typical High
$1,819.70

Where Massachusetts sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 17th of 51

$794

AK $1,778WY $479

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.