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Prenatal Blood Screen For Three Trisomies

Indiana rates for HCPCS 0327U

Screens a pregnancy for three chromosome conditions: trisomy 21 (Down syndrome), trisomy 18 and trisomy 13. A blood sample from the pregnant person is used, because it carries small amounts of DNA from the placenta, and the result is a risk estimate for each condition. Reporting of fetal sex is an optional addition.

Rates data updated July 2026.

How much does Prenatal Blood Screen For Three Trisomies cost?

$661

Typical negotiated rate. In Indiana, July 2026.

Insurers have agreed to pay about $661 for this service. The price depends on where it is billed: about $646 from a physician practice, and about $912 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$646$631 to $661
FacilityA hospital or hospital-owned outpatient department$912$794 to $1,738

How much rates vary

Facilitymedian $912 · 10th to 90th $794 to $2,399Professionalmedian $646 · 10th to 90th $501 to $871
$500$1K$2K$5K$10Kfacility $912professional $646

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$794.33
Median
$1,230.27
Typical High
$2,398.83
Aetna
Setting
Professional
Modifier
Global
Typical Low
$630.96
Median
$645.65
Typical High
$691.83
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$794.33
Median
$794.33
Typical High
$2,398.83
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$501.19
Median
$645.65
Typical High
$1,023.29
CareSource
Setting
Facility
Modifier
Global
Typical Low
$776.25
Median
$11,481.54
Typical High
$17,378.01
Cigna
Setting
Facility
Modifier
Global
Typical Low
$512.86
Median
$1,318.26
Typical High
$3,090.30
Cigna
Setting
Professional
Modifier
Global
Typical Low
$912.01
Median
$977.24
Typical High
$2,398.83
United
Setting
Facility
Modifier
Global
Typical Low
$794.33
Median
$794.33
Typical High
$954.99
United
Setting
Professional
Modifier
Global
Typical Low
$331.13
Median
$478.63
Typical High
$870.96

Where Indiana sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Indiana· 31st of 51

$661

AK $1,778WY $479

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.