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Prenatal Blood Screen For Three Trisomies

Illinois rates for HCPCS 0327U

Screens a pregnancy for three chromosome conditions: trisomy 21 (Down syndrome), trisomy 18 and trisomy 13. A blood sample from the pregnant person is used, because it carries small amounts of DNA from the placenta, and the result is a risk estimate for each condition. Reporting of fetal sex is an optional addition.

Rates data updated July 2026.

How much does Prenatal Blood Screen For Three Trisomies cost?

$741

Typical negotiated rate. In Illinois, July 2026.

Insurers have agreed to pay about $741 for this service. The price depends on where it is billed: about $646 from a physician practice, and about $1,202 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$646$589 to $759
FacilityA hospital or hospital-owned outpatient department$1,202$813 to $1,585

How much rates vary

Facilitymedian $1,202 · 10th to 90th $646 to $1,698Professionalmedian $646 · 10th to 90th $437 to $1,380
$500$1K$2Kfacility $1,202professional $646

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$645.65
Median
$1,202.26
Typical High
$1,621.81
Aetna
Setting
Professional
Modifier
Global
Typical Low
$489.78
Median
$645.65
Typical High
$1,621.81
BCBS
Setting
Facility
Modifier
Global
Typical Low
$954.99
Median
$1,071.52
Typical High
$1,288.25
Cigna
Setting
Facility
Modifier
Global
Typical Low
$933.25
Median
$1,737.80
Typical High
$3,981.07
Cigna
Setting
Professional
Modifier
Global
Typical Low
$933.25
Median
$977.24
Typical High
$1,148.15
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$346.74
Median
$1,071.52
Typical High
$1,479.11
Hally Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$1,023.29
Median
$1,023.29
Typical High
$1,023.29
United
Setting
Facility
Modifier
Global
Typical Low
$398.11
Median
$954.99
Typical High
$1,584.89
United
Setting
Professional
Modifier
Global
Typical Low
$331.13
Median
$478.63
Typical High
$794.33

Where Illinois sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 22nd of 51

$741

AK $1,778WY $479

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.