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Prenatal Blood Screen For Three Trisomies

Florida rates for HCPCS 0327U

Screens a pregnancy for three chromosome conditions: trisomy 21 (Down syndrome), trisomy 18 and trisomy 13. A blood sample from the pregnant person is used, because it carries small amounts of DNA from the placenta, and the result is a risk estimate for each condition. Reporting of fetal sex is an optional addition.

Rates data updated July 2026.

How much does Prenatal Blood Screen For Three Trisomies cost?

$575

Typical negotiated rate. In Florida, July 2026.

Insurers have agreed to pay about $575 for this service. The price depends on where it is billed: about $562 from a physician practice, and about $1,479 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$562$479 to $646
FacilityA hospital or hospital-owned outpatient department$1,479$708 to $2,291

How much rates vary

Facilitymedian $1,479 · 10th to 90th $550 to $4,266Professionalmedian $562 · 10th to 90th $447 to $794
$200$500$1K$2K$5Kfacility $1,479professional $562

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$575.44
Median
$1,905.46
Typical High
$4,265.80
Aetna
Setting
Professional
Modifier
Global
Typical Low
$478.63
Median
$562.34
Typical High
$707.95
AvMed
Setting
Professional
Modifier
Global
Typical Low
$630.96
Median
$794.33
Typical High
$794.33
Cigna
Setting
Facility
Modifier
Global
Typical Low
$407.38
Median
$602.56
Typical High
$3,235.94
Cigna
Setting
Professional
Modifier
Global
Typical Low
$977.24
Median
$1,148.15
Typical High
$3,801.89
Florida Blue
Setting
Facility
Modifier
Global
Typical Low
$1,479.11
Median
$1,479.11
Typical High
$1,479.11
Florida Blue
Setting
Professional
Modifier
Global
Typical Low
$478.63
Median
$478.63
Typical High
$676.08
Molina
Setting
Professional
Modifier
Global
Typical Low
$478.63
Median
$645.65
Typical High
$794.33
United
Setting
Facility
Modifier
Global
Typical Low
$331.13
Median
$707.95
Typical High
$977.24
United
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$338.84
Typical High
$1,047.13
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$478.63
Median
$478.63
Typical High
$794.33

Where Florida sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Florida· 47th of 51

$575

AK $1,778WY $479

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.