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Blood Tumor DNA Panel With MSI And TMB

North Carolina rates for HCPCS 0326U

Guides treatment choice in solid tumors from a blood sample rather than tumor tissue. Fragments of tumor DNA circulating in the blood are sequenced across at least eighty-three genes, and microsatellite instability and tumor mutational burden are reported as well — two measures counted beyond that gene total.

Rates data updated October 2026.

How much does Blood Tumor DNA Panel With MSI And TMB cost?

$5,012

Typical negotiated rate. In North Carolina, October 2026.

Insurers have agreed to pay about $5,012 for this service. The price depends on where it is billed: about $5,012 from a physician practice, and about $7,943 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$5,012$4,266 to $7,943
FacilityA hospital or hospital-owned outpatient department$7,943$3,981 to $22,909

How much rates vary

Facilitymedian $7,943 · 10th to 90th $3,981 to $22,909Professionalmedian $5,012 · 10th to 90th $3,236 to $13,183
$2K$5K$10K$20Kfacility $7,943professional $5,012

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$3,981.07
Median
$3,981.07
Typical High
$3,981.07
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$3,890.45
Median
$3,981.07
Typical High
$4,786.30
BCBS North Carolina
Setting
Professional
Modifier
None (both parts)
Typical Low
$4,265.80
Median
$5,495.41
Typical High
$15,848.93
Cigna
Setting
Facility
Modifier
None
Typical Low
$7,413.10
Median
$15,135.61
Typical High
$22,908.68
Medcost
Setting
Facility
Modifier
None
Typical Low
$3,981.07
Median
$3,981.07
Typical High
$5,888.44
Medcost
Setting
Professional
Modifier
None (both parts)
Typical Low
$5,011.87
Median
$5,011.87
Typical High
$8,511.38
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$2,089.30
Median
$3,019.95
Typical High
$5,128.61
10 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$1,949.84
Median
$1,995.26
Typical High
$2,344.23
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$776.25
Median
$794.33
Typical High
$954.99
Medcost
Setting
Professional
Modifier
26 · Professional part
Typical Low
$1,995.26
Median
$1,995.26
Typical High
$3,715.35
Medcost
Setting
Professional
Modifier
50 · Both sides
Typical Low
$7,585.78
Median
$7,585.78
Typical High
$19,054.61
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$2,511.89
Median
$2,511.89
Typical High
$6,456.54
Medcost
Setting
Professional
Modifier
80 · Assistant surgeon
Typical Low
$1,000.00
Median
$1,000.00
Typical High
$2,570.40
Medcost
Setting
Professional
Modifier
81 · Minimal assistant surgeon
Typical Low
$707.95
Median
$707.95
Typical High
$1,819.70
Medcost
Setting
Professional
Modifier
82 · Assistant surgeon, no resident
Typical Low
$707.95
Median
$707.95
Typical High
$1,819.70
Medcost
Setting
Professional
Modifier
AS · PA/NP assist
Typical Low
$707.95
Median
$707.95
Typical High
$1,819.70
Medcost
Setting
Professional
Modifier
TC · Technical part
Typical Low
$4,677.35
Median
$4,677.35
Typical High
$8,511.38

Where North Carolina sits

The same service costs 12.0 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 21st of 51

$5,012

TX $25,119AL $2,089

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.