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Blood Tumor DNA Panel With MSI And TMB

Colorado rates for HCPCS 0326U

Guides treatment choice in solid tumors from a blood sample rather than tumor tissue. Fragments of tumor DNA circulating in the blood are sequenced across at least eighty-three genes, and microsatellite instability and tumor mutational burden are reported as well — two measures counted beyond that gene total.

Rates data updated October 2026.

How much does Blood Tumor DNA Panel With MSI And TMB cost?

$6,918

Typical negotiated rate. In Colorado, October 2026.

Insurers have agreed to pay about $6,918 for this service. The price depends on where it is billed: about $3,020 from a physician practice, and about $14,791 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$3,020$2,089 to $6,457
FacilityA hospital or hospital-owned outpatient department$14,791$10,000 to $17,378

How much rates vary

Facilitymedian $14,791 · 10th to 90th $3,890 to $22,909Professionalmedian $3,020 · 10th to 90th $2,089 to $10,233
$2K$5K$10K$20Kfacility $14,791professional $3,020

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$5,011.87
Median
$10,471.29
Typical High
$22,908.68
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$3,715.35
Median
$3,801.89
Typical High
$5,011.87
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$6,606.93
Median
$15,135.61
Typical High
$22,908.68
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$2,089.30
Median
$2,089.30
Typical High
$10,964.78
Cigna
Setting
Facility
Modifier
None
Typical Low
$2,691.53
Median
$3,548.13
Typical High
$15,848.93
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$6,165.95
Median
$7,244.36
Typical High
$7,244.36
Denver HMP
Setting
Facility
Modifier
None
Typical Low
$3,801.89
Median
$4,466.84
Typical High
$6,918.31
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$5,011.87
Median
$7,079.46
Typical High
$10,232.93
Select Health
Setting
Facility
Modifier
None
Typical Low
$5,011.87
Median
$9,332.54
Typical High
$10,471.29
Select Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$3,467.37
Median
$5,011.87
Typical High
$7,585.78
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$2,089.30
Median
$2,089.30
Typical High
$3,715.35
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$3,715.35
Median
$3,801.89
Typical High
$3,981.07
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$1,862.09
Median
$1,905.46
Typical High
$2,630.27
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$758.58
Median
$758.58
Typical High
$1,071.52

Where Colorado sits

The same service costs 12.0 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 5th of 51

$6,918

TX $25,119AL $2,089

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.