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Paired Tumor Genome Sequencing With Optical Mapping

Massachusetts rates for HCPCS 0300U

Searches a cancer's complete genome for the changes driving it, in any type of tumor. Fresh tissue, blood or a bone-marrow sample is both sequenced across the whole genome and examined by optical genome mapping, which images very long DNA molecules to reveal large rearrangements, and the findings are compared against the patient's own normal tissue so that only cancer-specific changes are reported. It is the member of this family of tests that uses both techniques together.

Rates data updated October 2026.

How much does Paired Tumor Genome Sequencing With Optical Mapping cost?

$4,169

Typical negotiated rate. In Massachusetts, October 2026.

Insurers have agreed to pay about $4,169 for this service. The price depends on where it is billed: about $4,169 from a physician practice, and about $6,026 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$4,169$2,512 to $10,471
FacilityA hospital or hospital-owned outpatient department$6,026$3,631 to $9,772

How much rates vary

Facilitymedian $6,026 · 10th to 90th $2,951 to $12,882Professionalmedian $4,169 · 10th to 90th $2,512 to $20,893
$100$500$2K$10Kfacility $6,026professional $4,169

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$2,951.21
Median
$5,888.44
Typical High
$13,182.57
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$2,951.21
Median
$2,951.21
Typical High
$2,951.21
AllWays Health Partners
Setting
Facility
Modifier
None
Typical Low
$4,570.88
Median
$10,715.19
Typical High
$14,454.40
AllWays Health Partners
Setting
Professional
Modifier
None (both parts)
Typical Low
$2,511.89
Median
$8,709.64
Typical High
$20,892.96
AllWays Health Partners
Setting
Professional
Modifier
TC · Technical part
Typical Low
$20,892.96
Median
$20,892.96
Typical High
$20,892.96
Cigna
Setting
Facility
Modifier
None
Typical Low
$2,818.38
Median
$3,162.28
Typical High
$7,413.10
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$6,760.83
Median
$6,760.83
Typical High
$8,511.38
Fallon Health
Setting
Facility
Modifier
None
Typical Low
$83.18
Median
$6,025.60
Typical High
$7,079.46
Fallon Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$6,025.60
Median
$6,025.60
Typical High
$7,079.46
Harvard Pilgrim
Setting
Professional
Modifier
None (both parts)
Typical Low
$2,511.89
Median
$4,168.69
Typical High
$7,943.28
Mass General Brigham
Setting
Facility
Modifier
None
Typical Low
$4,570.88
Median
$10,715.19
Typical High
$14,454.40
Mass General Brigham
Setting
Professional
Modifier
None (both parts)
Typical Low
$2,511.89
Median
$8,709.64
Typical High
$20,892.96
Mass General Brigham
Setting
Professional
Modifier
TC · Technical part
Typical Low
$20,892.96
Median
$20,892.96
Typical High
$20,892.96
United
Setting
Facility
Modifier
None
Typical Low
$3,801.89
Median
$4,168.69
Typical High
$5,011.87
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$1,659.59
Median
$2,511.89
Typical High
$7,943.28
Well Sense
Setting
Facility
Modifier
None
Typical Low
$2,511.89
Median
$3,467.37
Typical High
$5,128.61
Well Sense
Setting
Professional
Modifier
None (both parts)
Typical Low
$2,511.89
Median
$2,511.89
Typical High
$3,019.95
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$1,479.11
Median
$1,479.11
Typical High
$1,479.11
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$588.84
Median
$588.84
Typical High
$588.84
Fallon Health
Setting
Facility
Modifier
QW · Waived lab test
Typical Low
$4,168.69
Median
$5,495.41
Typical High
$6,456.54

Where Massachusetts sits

The same service costs 67.6 times more in Texas than in Ohio. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 12th of 51

$4,169

TX $20,893OH $309

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.