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Paired Tumor Genome Sequencing With Optical Mapping

Iowa rates for HCPCS 0300U

Searches a cancer's complete genome for the changes driving it, in any type of tumor. Fresh tissue, blood or a bone-marrow sample is both sequenced across the whole genome and examined by optical genome mapping, which images very long DNA molecules to reveal large rearrangements, and the findings are compared against the patient's own normal tissue so that only cancer-specific changes are reported. It is the member of this family of tests that uses both techniques together.

Rates data updated July 2026.

Facilitymedian $6,310 · 10th–90th $3,236$12,0230%10%20%10th90th$6,310Professionalmedian $3,631 · 10th–90th $2,512$8,9130%10%20%10th90th$3,631$200.0$500.0$1.0K$2.0K$5.0K$10.0K$20.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$3,235.94
Median
$10,000.00
Typical High
$12,022.64
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,754.23
Median
$3,235.94
Typical High
$4,073.80
Cigna
Setting
Facility
Modifier
Global
Typical Low
$5,011.87
Median
$5,011.87
Typical High
$5,011.87
Cigna
Setting
Professional
Modifier
Global
Typical Low
$7,943.28
Median
$7,943.28
Typical High
$10,000.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$151.36
Median
$4,570.88
Typical High
$7,585.78
Medica
Setting
Facility
Modifier
Global
Typical Low
$4,168.69
Median
$5,011.87
Typical High
$11,481.54
Medica
Setting
Professional
Modifier
Global
Typical Low
$2,511.89
Median
$2,570.40
Typical High
$20,892.96
Midlands
Setting
Professional
Modifier
Global
Typical Low
$5,011.87
Median
$5,495.41
Typical High
$11,748.98
Midlands
Setting
Facility
Modifier
Global
Typical Low
$5,011.87
Median
$5,011.87
Typical High
$5,011.87
Oscar Health
Setting
Professional
Modifier
Global
Typical Low
$4,168.69
Median
$4,570.88
Typical High
$8,912.51
United
Setting
Facility
Modifier
Global
Typical Low
$4,168.69
Median
$4,168.69
Typical High
$9,332.54
United
Setting
Professional
Modifier
Global
Typical Low
$2,511.89
Median
$2,511.89
Typical High
$10,471.29
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$4,168.69
Median
$4,168.69
Typical High
$4,168.69