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Paired Tumor Genome Sequencing With Optical Mapping

Colorado rates for HCPCS 0300U

Searches a cancer's complete genome for the changes driving it, in any type of tumor. Fresh tissue, blood or a bone-marrow sample is both sequenced across the whole genome and examined by optical genome mapping, which images very long DNA molecules to reveal large rearrangements, and the findings are compared against the patient's own normal tissue so that only cancer-specific changes are reported. It is the member of this family of tests that uses both techniques together.

Rates data updated July 2026.

How much does Paired Tumor Genome Sequencing With Optical Mapping cost?

$6,026

Typical negotiated rate. In Colorado, July 2026.

Insurers have agreed to pay about $6,026 for this service. The price depends on where it is billed: about $3,162 from a physician practice, and about $11,482 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$3,162$2,630 to $3,548
FacilityA hospital or hospital-owned outpatient department$11,482$6,918 to $17,783

How much rates vary

Facilitymedian $11,482 · 10th to 90th $4,169 to $21,380Professionalmedian $3,162 · 10th to 90th $1,738 to $4,467
$200$500$1K$2K$5K$10K$20Kfacility $11,482professional $3,162

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$4,168.69
Median
$14,454.40
Typical High
$19,498.45
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,511.89
Median
$3,162.28
Typical High
$3,890.45
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$5,370.32
Median
$12,589.25
Typical High
$21,379.62
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$3,548.13
Typical High
$8,511.38
Cigna
Setting
Facility
Modifier
Global
Typical Low
$2,238.72
Median
$2,691.53
Typical High
$12,882.50
Cigna
Setting
Professional
Modifier
Global
Typical Low
$5,128.61
Median
$6,025.60
Typical High
$6,165.95
Denver HMP
Setting
Facility
Modifier
Global
Typical Low
$3,162.28
Median
$4,168.69
Typical High
$6,025.60
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$5,888.44
Median
$5,888.44
Typical High
$5,888.44
Select Health
Setting
Facility
Modifier
Global
Typical Low
$4,365.16
Median
$7,762.47
Typical High
$8,709.64
Select Health
Setting
Professional
Modifier
Global
Typical Low
$2,951.21
Median
$4,168.69
Typical High
$6,309.57
United
Setting
Facility
Modifier
Global
Typical Low
$3,801.89
Median
$4,365.16
Typical High
$6,309.57
United
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$1,737.80
Typical High
$3,090.30

Where Colorado sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 4th of 51

$6,026

AK $9,333WY $2,512

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.