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Paired Tumor Whole-Transcriptome RNA Analysis

Colorado rates for HCPCS 0298U

Examines the entire set of RNA a cancer is producing, in any type of tumor, to find the changes driving the disease. Fresh or preserved tumor tissue, blood or a bone-marrow sample is sequenced across the whole transcriptome and compared against the patient's own normal tissue, so that only cancer-specific findings are reported. That comparison covers sequence variants, how strongly genes are switched on, and fusion transcripts, all in one analysis.

Rates data updated October 2026.

How much does Paired Tumor Whole-Transcriptome RNA Analysis cost?

$3,981

Typical negotiated rate. In Colorado, October 2026.

Insurers have agreed to pay about $3,981 for this service. The price depends on where it is billed: about $1,738 from a physician practice, and about $8,511 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$1,738$1,230 to $3,802
FacilityA hospital or hospital-owned outpatient department$8,511$5,888 to $10,233

How much rates vary

Facilitymedian $8,511 · 10th to 90th $2,239 to $13,490Professionalmedian $1,738 · 10th to 90th $1,230 to $6,026
$200$500$1K$2K$5K$10K$20Kfacility $8,511professional $1,738

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$2,951.21
Median
$6,165.95
Typical High
$13,489.63
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$2,187.76
Median
$2,238.72
Typical High
$2,951.21
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$3,890.45
Median
$8,709.64
Typical High
$13,489.63
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$1,230.27
Median
$1,230.27
Typical High
$6,456.54
Cigna
Setting
Facility
Modifier
None
Typical Low
$1,698.24
Median
$2,570.40
Typical High
$9,120.11
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$3,548.13
Median
$4,265.80
Typical High
$4,265.80
Denver HMP
Setting
Facility
Modifier
None
Typical Low
$2,238.72
Median
$2,630.27
Typical High
$3,981.07
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$2,951.21
Median
$4,073.80
Typical High
$6,025.60
Select Health
Setting
Facility
Modifier
None
Typical Low
$2,951.21
Median
$5,370.32
Typical High
$6,165.95
Select Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$2,041.74
Median
$2,951.21
Typical High
$4,365.16
United
Setting
Facility
Modifier
None
Typical Low
$3,467.37
Median
$3,467.37
Typical High
$3,467.37
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$1,230.27
Median
$1,230.27
Typical High
$2,137.96
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$2,187.76
Median
$2,238.72
Typical High
$2,344.23
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$1,096.48
Median
$1,122.02
Typical High
$1,445.44
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$436.52
Median
$446.68
Typical High
$588.84

Where Colorado sits

The same service costs 30.9 times more in Texas than in Ohio. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 5th of 51

$3,981

TX $14,454OH $468

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.