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Paired Tumor Whole Genome Sequencing

Maryland rates for HCPCS 0297U

Searches a cancer's complete genome for the changes driving it, in any type of tumor. Fresh or preserved tumor tissue, blood or a bone-marrow sample is sequenced across the whole genome and compared against the patient's own normal tissue, so that only cancer-specific changes are reported. It uses genome sequencing on its own and accepts the widest choice of sample types in this family of paired tests.

Rates data updated July 2026.

How much does Paired Tumor Whole Genome Sequencing cost?

$2,188

Typical negotiated rate. In Maryland, July 2026.

Insurers have agreed to pay about $2,188 for this service. Most negotiated rates run $1,905 to $2,399.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $1,230 · 10th to 90th $1,230 to $2,239Professionalmedian $2,188 · 10th to 90th $1,318 to $2,570
$1.0K$2.0K$5.0Kfacility $1,230professional $2,188

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,905.46
Median
$2,187.76
Typical High
$2,454.71
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$2,089.30
Median
$2,089.30
Typical High
$2,630.27
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$2,951.21
Median
$3,388.44
Typical High
$4,365.16
United
Setting
Facility
Modifier
Global
Typical Low
$1,230.27
Median
$1,230.27
Typical High
$2,238.72
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,318.26
Typical High
$2,570.40
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$1,445.44
Median
$1,445.44
Typical High
$1,445.44

Where Maryland sits

The same service costs 3.8 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Maryland $2,188 · 42nd of 51
AK $6,607WY $1,738

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.