Prenatal Trisomy Screening From Blood

Nationwide rates for HCPCS 0168U

Screens a pregnancy for the three most common chromosome conditions, trisomy 21 (Down syndrome), trisomy 18 and trisomy 13, using DNA fragments found in the pregnant person's blood plasma. It reports a risk figure and, unlike some similar tests, runs without requiring a minimum amount of DNA from the pregnancy in the sample.

Rates data updated July 2026.

How much does Prenatal Trisomy Screening From Blood cost?

$1,862

Typical negotiated rate. Nationwide, July 2026.

Insurers have agreed to pay about $1,862 for this service. The price depends on where it is billed: about $1,479 from a physician practice, and about $1,862 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 16 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed by	Who charges it	Typical	Range
Physician practiceA doctor's office, clinic or independent provider	A doctor's office, clinic or independent provider	$1,479	$603 to $3,388
FacilityA hospital or hospital-owned outpatient department	A hospital or hospital-owned outpatient department	$1,862	$1,096 to $1,862

How much rates vary

Facilitymedian $1,862 · 10th to 90th $759 to $25,704Professionalmedian $1,479 · 10th to 90th $316 to $3,388

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier	Facility/Professional	Modifier	Typical Low	Median	Typical High
United Setting Facility Modifier Global Typical Low $457.09 Median $758.58 Typical High $831.76	Facility	Global	$457.09	$758.58	$831.76
United Setting Professional Modifier Global Typical Low $30.90 Median $316.23 Typical High $977.24	Professional	Global	$30.90	$316.23	$977.24

What it costs in each state

The same service costs 1737.8 times more in Indiana than in South Carolina. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Touch or drag across the chart to see any state's rate.

IN $52,481SC $30.20

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.