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MLH1 Gene RNA Analysis

Indiana rates for HCPCS 0158U

Examines MLH1, one of the mismatch repair genes involved in Lynch syndrome, by reading its RNA, the working copy of the gene. It is added to a main genetic test to help decide whether an MLH1 change actually affects how the gene works.

Rates data updated July 2026.

How much does MLH1 Gene RNA Analysis cost?

$282

Typical negotiated rate. In Indiana, July 2026.

Insurers have agreed to pay about $282 for this service. The price depends on where it is billed: about $234 from a physician practice, and about $324 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$234$234 to $288
FacilityA hospital or hospital-owned outpatient department$324$282 to $617

How much rates vary

Facilitymedian $324 · 10th to 90th $282 to $851Professionalmedian $234 · 10th to 90th $191 to $347
$200$500$1K$2Kfacility $324professional $234

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$281.84
Median
$436.52
Typical High
$851.14
Aetna
Setting
Professional
Modifier
Global
Typical Low
$223.87
Median
$234.42
Typical High
$245.47
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$281.84
Median
$288.40
Typical High
$851.14
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$288.40
Typical High
$446.68
CareSource
Setting
Facility
Modifier
Global
Typical Low
$275.42
Median
$4,073.80
Typical High
$6,165.95
Cigna
Setting
Facility
Modifier
Global
Typical Low
$181.97
Median
$467.74
Typical High
$1,096.48
Cigna
Setting
Professional
Modifier
Global
Typical Low
$323.59
Median
$380.19
Typical High
$851.14
United
Setting
Facility
Modifier
Global
Typical Low
$281.84
Median
$281.84
Typical High
$338.84
United
Setting
Professional
Modifier
Global
Typical Low
$117.49
Median
$169.82
Typical High
$309.03

Where Indiana sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Indiana· 28th of 51

$282

AK $631WY $170

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.