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Sickle Cell Adhesion Test, VCAM-1

South Dakota rates for HCPCS 0121U

Measures how strongly a person's blood cells stick to VCAM-1, a protein on the lining of blood vessels, using a whole blood sample. Sticking of this kind contributes to the blockages seen in sickle cell disease. A companion test measures adhesion to P-selectin instead.

Rates data updated July 2026.

How much does Sickle Cell Adhesion Test, VCAM-1 cost?

$977

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $977 for this service. The price depends on where it is billed: about $977 from a physician practice, and about $977 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$977$589 to $1,230
FacilityA hospital or hospital-owned outpatient department$977$977 to $977

How much rates vary

Facilitymedian $977 · 10th to 90th $575 to $977Professionalmedian $977 · 10th to 90th $309 to $1,413
$200$500$1K$2Kfacility $977professional $977

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$354.81
Median
$575.44
Typical High
$575.44
Aetna
Setting
Professional
Modifier
Global
Typical Low
$354.81
Median
$354.81
Typical High
$354.81
Cigna
Setting
Facility
Modifier
Global
Typical Low
$977.24
Median
$977.24
Typical High
$977.24
Cigna
Setting
Professional
Modifier
Global
Typical Low
$724.44
Median
$977.24
Typical High
$1,230.27
Medica
Setting
Facility
Modifier
Global
Typical Low
$478.63
Median
$575.44
Typical High
$2,398.83
Medica
Setting
Professional
Modifier
Global
Typical Low
$257.04
Median
$257.04
Typical High
$616.60
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$724.44
Median
$1,202.26
Typical High
$1,412.54
United
Setting
Facility
Modifier
Global
Typical Low
$616.60
Median
$616.60
Typical High
$616.60
United
Setting
Professional
Modifier
Global
Typical Low
$213.80
Median
$309.03
Typical High
$676.08
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$512.86
Median
$512.86
Typical High
$512.86

Where South Dakota sits

The same service costs 3.0 times more in South Dakota than in Connecticut. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 1st of 51

$977

SD $977CT $331

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.