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Sickle Cell Adhesion Test, VCAM-1

Pennsylvania rates for HCPCS 0121U

Measures how strongly a person's blood cells stick to VCAM-1, a protein on the lining of blood vessels, using a whole blood sample. Sticking of this kind contributes to the blockages seen in sickle cell disease. A companion test measures adhesion to P-selectin instead.

Rates data updated July 2026.

How much does Sickle Cell Adhesion Test, VCAM-1 cost?

$437

Typical negotiated rate. In Pennsylvania, July 2026.

Insurers have agreed to pay about $437 for this service. The price depends on where it is billed: about $417 from a physician practice, and about $776 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$417$331 to $437
FacilityA hospital or hospital-owned outpatient department$776$513 to $1,023

How much rates vary

Facilitymedian $776 · 10th to 90th $437 to $1,738Professionalmedian $417 · 10th to 90th $269 to $562
$200$500$1Kfacility $776professional $417

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$436.52
Median
$977.24
Typical High
$1,819.70
Aetna
Setting
Professional
Modifier
Global
Typical Low
$269.15
Median
$416.87
Typical High
$436.52
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$398.11
Median
$398.11
Typical High
$398.11
Cigna
Setting
Facility
Modifier
Global
Typical Low
$363.08
Median
$776.25
Typical High
$1,737.80
Cigna
Setting
Professional
Modifier
Global
Typical Low
$588.84
Median
$588.84
Typical High
$724.44
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$239.88
Median
$302.00
Typical High
$741.31
Geisinger
Setting
Facility
Modifier
Global
Typical Low
$512.86
Median
$512.86
Typical High
$512.86
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$436.52
Median
$512.86
Typical High
$891.25
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$537.03
Median
$977.24
Typical High
$1,819.70
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$331.13
Median
$416.87
Typical High
$1,258.93
UPMC Health Plan
Setting
Facility
Modifier
Global
Typical Low
$512.86
Median
$562.34
Typical High
$1,258.93
UPMC Health Plan
Setting
Professional
Modifier
Global
Typical Low
$446.68
Median
$512.86
Typical High
$562.34
United
Setting
Facility
Modifier
Global
Typical Low
$257.04
Median
$512.86
Typical High
$616.60
United
Setting
Professional
Modifier
Global
Typical Low
$213.80
Median
$323.59
Typical High
$758.58

Where Pennsylvania sits

The same service costs 3.0 times more in South Dakota than in Connecticut. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Pennsylvania· 35th of 51

$437

SD $977CT $331

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.