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Sickle Cell Adhesion Test, VCAM-1

Massachusetts rates for HCPCS 0121U

Measures how strongly a person's blood cells stick to VCAM-1, a protein on the lining of blood vessels, using a whole blood sample. Sticking of this kind contributes to the blockages seen in sickle cell disease. A companion test measures adhesion to P-selectin instead.

Rates data updated July 2026.

How much does Sickle Cell Adhesion Test, VCAM-1 cost?

$513

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $513 for this service. The price depends on where it is billed: about $513 from a physician practice, and about $891 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$513$380 to $513
FacilityA hospital or hospital-owned outpatient department$891$513 to $1,479

How much rates vary

Facilitymedian $891 · 10th to 90th $355 to $2,188Professionalmedian $513 · 10th to 90th $309 to $1,023
$200$500$1K$2K$5Kfacility $891professional $513

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$354.81
Median
$891.25
Typical High
$1,479.11
Aetna
Setting
Professional
Modifier
Global
Typical Low
$331.13
Median
$354.81
Typical High
$416.87
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$2,398.83
Median
$2,398.83
Typical High
$2,398.83
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$309.03
Typical High
$758.58
Cigna
Setting
Facility
Modifier
Global
Typical Low
$354.81
Median
$691.83
Typical High
$1,778.28
Cigna
Setting
Professional
Modifier
Global
Typical Low
$588.84
Median
$616.60
Typical High
$776.25
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$4,897.79
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$741.31
Median
$741.31
Typical High
$870.96
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$512.86
Median
$512.86
Typical High
$1,096.48
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$2,398.83
Median
$2,398.83
Typical High
$2,398.83
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$309.03
Typical High
$758.58
United
Setting
Facility
Modifier
Global
Typical Low
$309.03
Median
$512.86
Typical High
$616.60
United
Setting
Professional
Modifier
Global
Typical Low
$309.03
Median
$512.86
Typical High
$1,380.38

Where Massachusetts sits

The same service costs 3.0 times more in South Dakota than in Connecticut. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 17th of 51

$513

SD $977CT $331

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.