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Sickle Cell Adhesion Test, VCAM-1

Colorado rates for HCPCS 0121U

Measures how strongly a person's blood cells stick to VCAM-1, a protein on the lining of blood vessels, using a whole blood sample. Sticking of this kind contributes to the blockages seen in sickle cell disease. A companion test measures adhesion to P-selectin instead.

Rates data updated October 2026.

How much does Sickle Cell Adhesion Test, VCAM-1 cost?

$617

Typical negotiated rate. In Colorado, October 2026.

Insurers have agreed to pay about $617 for this service. The price depends on where it is billed: about $347 from a physician practice, and about $1,479 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$347$214 to $389
FacilityA hospital or hospital-owned outpatient department$1,479$1,023 to $1,778

How much rates vary

Facilitymedian $1,479 · 10th to 90th $389 to $2,344Professionalmedian $347 · 10th to 90th $214 to $977
$100$200$500$1K$2Kfacility $1,479professional $347

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$512.86
Median
$1,071.52
Typical High
$2,398.83
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$354.81
Median
$416.87
Typical High
$2,344.23
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$676.08
Median
$1,513.56
Typical High
$2,344.23
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$213.80
Median
$346.74
Typical High
$1,047.13
Cigna
Setting
Facility
Modifier
None
Typical Low
$295.12
Median
$446.68
Typical High
$1,621.81
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$346.74
Median
$616.60
Typical High
$741.31
Denver HMP
Setting
Facility
Modifier
None
Typical Low
$389.05
Median
$457.09
Typical High
$676.08
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$407.38
Median
$724.44
Typical High
$1,071.52
Select Health
Setting
Facility
Modifier
None
Typical Low
$512.86
Median
$933.25
Typical High
$1,071.52
Select Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$354.81
Median
$354.81
Typical High
$512.86
United
Setting
Facility
Modifier
None
Typical Low
$616.60
Median
$616.60
Typical High
$616.60
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$213.80
Median
$213.80
Typical High
$380.19
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$380.19
Median
$389.05
Typical High
$478.63
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$190.55
Median
$194.98
Typical High
$257.04
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$75.86
Median
$77.62
Typical High
$102.33

Where Colorado sits

The same service costs 4.5 times more in Alaska than in Mississippi. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 8th of 51

$617

AK $955MS $214

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.