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Inherited Opioid Dependence Risk Panel

Pennsylvania rates for HCPCS 0078U

Estimates a person's inherited susceptibility to opioid use disorder. It examines 16 variants across genes involved in opioid and brain signaling — OPRM1, OPRK1, COMT, DRD2, DRD4, HTR2A, ABCB1 and MTHFR — in cells collected on a swab, and reports a risk classification.

Rates data updated July 2026.

How much does Inherited Opioid Dependence Risk Panel cost?

$355

Typical negotiated rate. In Pennsylvania, July 2026.

Insurers have agreed to pay about $355 for this service. Most negotiated rates run $355 to $447.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $501 · 10th to 90th $447 to $57,544Professionalmedian $355 · 10th to 90th $339 to $575
$500$1K$2K$5K$10K$20K$50Kfacility $501professional $355

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Capital Blue Cross
Setting
Facility
Modifier
Global
Typical Low
$5,011.87
Median
$8,511.38
Typical High
$77,624.71
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$354.81
Median
$354.81
Typical High
$354.81
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$338.84
Median
$338.84
Typical High
$478.63
Oscar Health
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$660.69
Typical High
$912.01
UPMC Health Plan
Setting
Facility
Modifier
Global
Typical Low
$446.68
Median
$446.68
Typical High
$501.19
UPMC Health Plan
Setting
Professional
Modifier
Global
Typical Low
$446.68
Median
$446.68
Typical High
$501.19
United
Setting
Professional
Modifier
Global
Typical Low
$524.81
Median
$549.54
Typical High
$676.08

Where Pennsylvania sits

The same service costs 12.3 times more in New Jersey than in Utah. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Pennsylvania· 38th of 40

$355

NJ $3,311UT $269

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.