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Inherited Opioid Dependence Risk Panel

Pennsylvania rates for HCPCS 0078U

Estimates a person's inherited susceptibility to opioid use disorder. It examines 16 variants across genes involved in opioid and brain signaling — OPRM1, OPRK1, COMT, DRD2, DRD4, HTR2A, ABCB1 and MTHFR — in cells collected on a swab, and reports a risk classification.

Rates data updated July 2026.

Facilitymedian $501 · 10th–90th $447$57,5440%20%10th90th$501Professionalmedian $355 · 10th–90th $339$5750%20%40%10th90th$355$100.0$500.0$2.0K$10.0K$50.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Small sample; interpret with caution. Need provider-level prices? Contact us.

Insurance Carrier
Capital Blue Cross
Setting
Facility
Modifier
Global
Typical Low
$5,011.87
Median
$8,511.38
Typical High
$77,624.71
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$354.81
Median
$354.81
Typical High
$354.81
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$338.84
Median
$338.84
Typical High
$478.63
Oscar Health
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$660.69
Typical High
$912.01
UPMC Health Plan
Setting
Facility
Modifier
Global
Typical Low
$446.68
Median
$446.68
Typical High
$501.19
UPMC Health Plan
Setting
Professional
Modifier
Global
Typical Low
$446.68
Median
$446.68
Typical High
$501.19
United
Setting
Professional
Modifier
Global
Typical Low
$524.81
Median
$549.54
Typical High
$676.08