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Inherited Opioid Dependence Risk Panel

Massachusetts rates for HCPCS 0078U

Estimates a person's inherited susceptibility to opioid use disorder. It examines 16 variants across genes involved in opioid and brain signaling — OPRM1, OPRK1, COMT, DRD2, DRD4, HTR2A, ABCB1 and MTHFR — in cells collected on a swab, and reports a risk classification.

Rates data updated July 2026.

How much does Inherited Opioid Dependence Risk Panel cost?

$1,096

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $1,096 for this service. The price depends on where it is billed: about $2,239 from a physician practice, and about $1,096 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

Few insurers publish rates for this combination, so treat this figure as a rough guide.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,239$661 to $2,239
FacilityA hospital or hospital-owned outpatient department$1,096$447 to $1,096

How much rates vary

Facilitymedian $1,096 · 10th to 90th $269 to $1,096Professionalmedian $2,239 · 10th to 90th $550 to $2,239
$500$1K$2Kfacility $1,096professional $2,239

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$1,096.48
Median
$1,096.48
Typical High
$1,096.48
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$2,238.72
Median
$2,238.72
Typical High
$2,238.72
Cigna
Setting
Professional
Modifier
Global
Typical Low
$549.54
Median
$549.54
Typical High
$691.83
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$1,096.48
Median
$1,096.48
Typical High
$1,096.48
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$2,238.72
Median
$2,238.72
Typical High
$2,238.72
United
Setting
Facility
Modifier
Global
Typical Low
$269.15
Median
$269.15
Typical High
$446.68
United
Setting
Professional
Modifier
Global
Typical Low
$549.54
Median
$549.54
Typical High
$977.24

Where Massachusetts sits

The same service costs 12.3 times more in New Jersey than in Utah. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 5th of 40

$1,096

NJ $3,311UT $269

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.