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Monoclonal Protein Detection By Mass Spectrometry

Pennsylvania rates for HCPCS 0077U

Looks for a monoclonal protein — an abnormal antibody made by a single clone of plasma cells — in someone being checked for a plasma cell disorder such as myeloma. The abnormal antibody is pulled out of the sample and identified by mass spectrometry, and the report also states which antibody class it belongs to. Blood or urine can be used.

Rates data updated July 2026.

Facilitymedian $68 · 10th–90th $37$1620%10%20%10th90th$68Professionalmedian $24 · 10th–90th $20$540%20%40%10th90th$24$20.0$50.0$100.0$200.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$37.15
Median
$67.61
Typical High
$162.18
Aetna
Setting
Professional
Modifier
Global
Typical Low
$19.95
Median
$19.95
Typical High
$37.15
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$33.88
Median
$33.88
Typical High
$33.88
Cigna
Setting
Facility
Modifier
Global
Typical Low
$42.66
Median
$67.61
Typical High
$147.91
Cigna
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$208.93
Typical High
$208.93
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$57.54
Typical High
$61.66
Geisinger
Setting
Facility
Modifier
Global
Typical Low
$43.65
Median
$43.65
Typical High
$43.65
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$46.77
Median
$72.44
Typical High
$109.65
Highmark BCBS
Setting
Facility
Modifier
Global
Typical Low
$87.10
Median
$87.10
Typical High
$107.15
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$40.74
Median
$109.65
Typical High
$162.18
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$19.95
Median
$34.67
Typical High
$109.65
UPMC Health Plan
Setting
Facility
Modifier
Global
Typical Low
$43.65
Median
$43.65
Typical High
$107.15
UPMC Health Plan
Setting
Professional
Modifier
Global
Typical Low
$43.65
Median
$43.65
Typical High
$47.86
United
Setting
Facility
Modifier
Global
Typical Low
$38.90
Median
$43.65
Typical High
$52.48
United
Setting
Professional
Modifier
Global
Typical Low
$18.20
Median
$26.30
Typical High
$64.57