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Solid Tumor 468-Gene Profile With Normal Match

South Carolina rates for HCPCS 0048U

Profiles the genetic changes in a solid tumor to inform cancer care. It sequences 468 genes in preserved tumor tissue and compares the result against a matched normal sample from the same person, so changes that arose in the cancer can be separated from ones present from birth.

Rates data updated July 2026.

How much does Solid Tumor 468-Gene Profile With Normal Match cost?

$2,344

Typical negotiated rate. In South Carolina, July 2026.

Insurers have agreed to pay about $2,344 for this service. The price depends on where it is billed: about $2,291 from a physician practice, and about $7,244 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,291$2,291 to $2,344
FacilityA hospital or hospital-owned outpatient department$7,244$2,291 to $9,333

How much rates vary

Facilitymedian $7,244 · 10th to 90th $2,291 to $13,804Professionalmedian $2,291 · 10th to 90th $1,738 to $2,512
$2K$5K$10Kfacility $7,244professional $2,291

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,290.87
Median
$7,244.36
Typical High
$13,803.84
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,290.87
Median
$2,290.87
Typical High
$2,398.83
BCBS
Setting
Professional
Modifier
Global
Typical Low
$2,951.21
Median
$3,090.30
Typical High
$6,025.60
Cigna
Setting
Facility
Modifier
Global
Typical Low
$5,495.41
Median
$9,549.93
Typical High
$16,595.87
Medcost
Setting
Facility
Modifier
Global
Typical Low
$2,238.72
Median
$2,630.27
Typical High
$5,248.07
United
Setting
Facility
Modifier
Global
Typical Low
$2,630.27
Median
$2,951.21
Typical High
$3,467.37
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$2,951.21

Where South Carolina sits

The same service costs 3.5 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 36th of 51

$2,344

AK $6,607NE $1,905

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.