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Solid Tumor 468-Gene Profile With Normal Match

Massachusetts rates for HCPCS 0048U

Profiles the genetic changes in a solid tumor to inform cancer care. It sequences 468 genes in preserved tumor tissue and compares the result against a matched normal sample from the same person, so changes that arose in the cancer can be separated from ones present from birth.

Rates data updated July 2026.

Facilitymedian $5,754 · 10th–90th $2,951$8,5110%10%10th90th$5,754Professionalmedian $2,951 · 10th–90th $1,738$4,6770%50%10th90th$2,951$100.0$500.0$2.0K$10.0K$50.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,041.74
Median
$5,011.87
Typical High
$8,511.38
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,584.89
Median
$2,041.74
Typical High
$2,344.23
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$3,235.94
Median
$7,079.46
Typical High
$13,803.84
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$2,951.21
Typical High
$9,772.37
BCBS
Setting
Facility
Modifier
Global
Typical Low
$4,677.35
Median
$5,754.40
Typical High
$8,317.64
Cigna
Setting
Facility
Modifier
Global
Typical Low
$2,089.30
Median
$2,290.87
Typical High
$4,677.35
Cigna
Setting
Professional
Modifier
Global
Typical Low
$3,548.13
Median
$3,548.13
Typical High
$4,466.84
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$5,011.87
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$4,168.69
Median
$4,168.69
Typical High
$5,011.87
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$2,951.21
Median
$2,951.21
Typical High
$4,677.35
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$3,235.94
Median
$7,079.46
Typical High
$13,803.84
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$2,951.21
Typical High
$9,772.37
United
Setting
Facility
Modifier
Global
Typical Low
$1,737.80
Median
$2,951.21
Typical High
$3,467.37
United
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$2,951.21
Typical High
$5,128.61