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BCR-ABL1 Major Breakpoint Measurement

Virginia rates for HCPCS 0040U

Used in chronic myeloid leukemia to measure how much of the abnormal BCR-ABL1 gene fusion is present, which shows how the disease is responding. It reports a quantity for the major breakpoint form of the fusion only; a companion test covers both breakpoint forms.

Rates data updated October 2026.

How much does BCR-ABL1 Major Breakpoint Measurement cost?

$282

Typical negotiated rate. In Virginia, October 2026.

Insurers have agreed to pay about $282 for this service. The price depends on where it is billed: about $200 from a physician practice, and about $513 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$200$81.28 to $331
FacilityA hospital or hospital-owned outpatient department$513$407 to $891

How much rates vary

Facilitymedian $513 · 10th to 90th $407 to $1,862Professionalmedian $200 · 10th to 90th $81 to $407
$50$100$200$500$1K$2Kfacility $513professional $200

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$309.03
Median
$389.05
Typical High
$1,071.52
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$309.03
Median
$309.03
Typical High
$389.05
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$407.38
Median
$407.38
Typical High
$1,995.26
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$81.28
Median
$81.28
Typical High
$281.84
CareFirst
Setting
Professional
Modifier
None (both parts)
Typical Low
$331.13
Median
$371.54
Typical High
$436.52
Cigna
Setting
Facility
Modifier
None
Typical Low
$416.87
Median
$794.33
Typical High
$1,230.27
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$269.15
Median
$269.15
Typical High
$269.15
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$389.05
Median
$446.68
Typical High
$575.44
Medcost
Setting
Facility
Modifier
None
Typical Low
$616.60
Median
$616.60
Typical High
$812.83
Medcost
Setting
Professional
Modifier
None (both parts)
Typical Low
$295.12
Median
$295.12
Typical High
$457.09
Sentara
Setting
Facility
Modifier
None
Typical Low
$288.40
Median
$512.86
Typical High
$691.83
Sentara
Setting
Professional
Modifier
None (both parts)
Typical Low
$288.40
Median
$562.34
Typical High
$794.33
United
Setting
Facility
Modifier
None
Typical Low
$489.78
Median
$489.78
Typical High
$489.78
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$173.78
Median
$245.47
Typical High
$575.44
1 more rate with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$309.03
Median
$309.03
Typical High
$389.05

Where Virginia sits

The same service costs 11.7 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 38th of 51

$282

TX $2,042AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.