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BCR-ABL1 Major Breakpoint Measurement

Iowa rates for HCPCS 0040U

Used in chronic myeloid leukemia to measure how much of the abnormal BCR-ABL1 gene fusion is present, which shows how the disease is responding. It reports a quantity for the major breakpoint form of the fusion only; a companion test covers both breakpoint forms.

Rates data updated July 2026.

How much does BCR-ABL1 Major Breakpoint Measurement cost?

$490

Typical negotiated rate. In Iowa, July 2026.

Insurers have agreed to pay about $490 for this service. The price depends on where it is billed: about $437 from a physician practice, and about $724 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$437$275 to $776
FacilityA hospital or hospital-owned outpatient department$724$407 to $1,072

How much rates vary

Facilitymedian $724 · 10th to 90th $407 to $1,175Professionalmedian $437 · 10th to 90th $245 to $1,047
$200$500$1K$2Kfacility $724professional $437

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$407.38
Median
$977.24
Typical High
$1,174.90
Aetna
Setting
Professional
Modifier
Global
Typical Low
$398.11
Median
$398.11
Typical High
$489.78
Cigna
Setting
Professional
Modifier
Global
Typical Low
$776.25
Median
$776.25
Typical High
$977.24
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$151.36
Median
$537.03
Typical High
$741.31
Medica
Setting
Facility
Modifier
Global
Typical Low
$407.38
Median
$489.78
Typical High
$1,096.48
Medica
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$457.09
Typical High
$1,819.70
Midlands
Setting
Professional
Modifier
Global
Typical Low
$489.78
Median
$489.78
Typical High
$501.19
Oscar Health
Setting
Professional
Modifier
Global
Typical Low
$398.11
Median
$446.68
Typical High
$870.96
United
Setting
Facility
Modifier
Global
Typical Low
$407.38
Median
$407.38
Typical High
$912.01
United
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$275.42
Typical High
$1,047.13
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$407.38
Median
$407.38
Typical High
$407.38

Where Iowa sits

The same service costs 11.2 times more in Alaska than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Iowa· 12th of 51

$490

AK $912KY $81.28

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.