go back

Prion Protein Detection In Spinal Fluid

Florida rates for HCPCS 0035U

Helps investigate suspected prion disease, a rare condition in which a brain protein misfolds and damages nerve tissue. It uses an amplification technique to detect misfolded prion protein in cerebrospinal fluid and reports whether it is present.

Rates data updated October 2026.

How much does Prion Protein Detection In Spinal Fluid cost?

$380

Typical negotiated rate. In Florida, October 2026.

Insurers have agreed to pay about $380 for this service. The price depends on where it is billed: about $324 from a physician practice, and about $1,000 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$324$245 to $389
FacilityA hospital or hospital-owned outpatient department$1,000$537 to $1,000

How much rates vary

Facilitymedian $1,000 · 10th to 90th $407 to $1,000Professionalmedian $324 · 10th to 90th $229 to $537
$20$50$100$200$500$1K$2Kfacility $1,000professional $324

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$389.05
Typical High
$1,096.48
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$323.59
Median
$354.81
Typical High
$436.52
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$323.59
Median
$354.81
Typical High
$457.09
AvMed
Setting
Facility
Modifier
None
Typical Low
$537.03
Median
$537.03
Typical High
$537.03
AvMed
Setting
Professional
Modifier
None (both parts)
Typical Low
$436.52
Median
$537.03
Typical High
$537.03
Cigna
Setting
Facility
Modifier
None
Typical Low
$309.03
Median
$457.09
Typical High
$2,187.76
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$436.52
Median
$616.60
Typical High
$776.25
Florida Blue
Setting
Facility
Modifier
None
Typical Low
$1,000.00
Median
$1,000.00
Typical High
$1,000.00
Florida Blue
Setting
Professional
Modifier
None (both parts)
Typical Low
$323.59
Median
$323.59
Typical High
$489.78
Molina
Setting
Professional
Modifier
None (both parts)
Typical Low
$371.54
Median
$371.54
Typical High
$380.19
United
Setting
Facility
Modifier
None
Typical Low
$537.03
Median
$537.03
Typical High
$537.03
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$190.55
Median
$229.09
Typical High
$537.03
Wellpoint
Setting
Professional
Modifier
None (both parts)
Typical Low
$323.59
Median
$323.59
Typical High
$537.03

Where Florida sits

The same service costs 16.6 times more in Wyoming than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Florida· 36th of 51

$380

WY $832GA $50.12

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.