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Ovarian Cancer Risk Blood Protein Test

Massachusetts rates for HCPCS 0003U

Estimates the likelihood that ovarian cancer is present. It measures five proteins in blood serum — apolipoprotein A-1, CA 125, follicle stimulating hormone, HE4 and transferrin — and combines them into a probability. No genetic material is tested.

Rates data updated October 2026.

How much does Ovarian Cancer Risk Blood Protein Test cost?

$955

Typical negotiated rate. In Massachusetts, October 2026.

Insurers have agreed to pay about $955 for this service. The price depends on where it is billed: about $955 from a physician practice, and about $1,349 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$955$575 to $3,090
FacilityA hospital or hospital-owned outpatient department$1,349$851 to $1,585

How much rates vary

Facilitymedian $1,349 · 10th to 90th $708 to $3,631Professionalmedian $955 · 10th to 90th $575 to $4,786
$100$200$500$1K$2K$5K$10Kfacility $1,349professional $955

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$660.69
Median
$1,318.26
Typical High
$2,951.21
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$660.69
Median
$660.69
Typical High
$660.69
AllWays Health Partners
Setting
Professional
Modifier
None (both parts)
Typical Low
$398.11
Median
$3,311.31
Typical High
$4,786.30
AllWays Health Partners
Setting
Professional
Modifier
TC · Technical part
Typical Low
$5,888.44
Median
$5,888.44
Typical High
$5,888.44
Cigna
Setting
Facility
Modifier
None
Typical Low
$630.96
Median
$741.31
Typical High
$1,659.59
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$549.54
Median
$549.54
Typical High
$1,445.44
Fallon Health
Setting
Facility
Modifier
None
Typical Low
$83.18
Median
$1,584.89
Typical High
$5,888.44
Fallon Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$1,348.96
Median
$1,348.96
Typical High
$1,584.89
Harvard Pilgrim
Setting
Professional
Modifier
None (both parts)
Typical Low
$575.44
Median
$954.99
Typical High
$2,570.40
Mass General Brigham
Setting
Professional
Modifier
None (both parts)
Typical Low
$398.11
Median
$3,311.31
Typical High
$4,786.30
Mass General Brigham
Setting
Professional
Modifier
TC · Technical part
Typical Low
$5,888.44
Median
$5,888.44
Typical High
$5,888.44
United
Setting
Facility
Modifier
None
Typical Low
$851.14
Median
$954.99
Typical High
$1,148.15
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$380.19
Median
$575.44
Typical High
$1,819.70
Well Sense
Setting
Facility
Modifier
None
Typical Low
$707.95
Median
$891.25
Typical High
$1,659.59
Well Sense
Setting
Professional
Modifier
None (both parts)
Typical Low
$2,511.89
Median
$2,511.89
Typical High
$3,019.95
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$331.13
Median
$331.13
Typical High
$331.13
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$131.83
Median
$131.83
Typical High
$131.83
Fallon Health
Setting
Facility
Modifier
QW · Waived lab test
Typical Low
$954.99
Median
$1,230.27
Typical High
$1,479.11

Where Massachusetts sits

The same service costs 8.3 times more in Texas than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 17th of 51

$955

TX $4,786KY $575

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.