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Targeted Gene Sequencing Analysis

South Carolina rates for HCPCS 81405

This laboratory analysis examines the DNA sequence of a specific gene associated with an inherited condition, looking for changes that could explain a patient's symptoms or family history. It is one of many single-gene analyzes available, each ordered based on the particular condition being evaluated. Results help confirm a diagnosis or guide further testing and family counseling.

Rates data updated October 2026.

How much does Targeted Gene Sequencing Analysis cost?

$302

Typical negotiated rate. In South Carolina, October 2026.

Insurers have agreed to pay about $302 for this service. The price depends on where it is billed: about $302 from a physician practice, and about $631 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$302$182 to $302
FacilityA hospital or hospital-owned outpatient department$631$316 to $1,380

How much rates vary

Facilitymedian $631 · 10th to 90th $234 to $1,862Professionalmedian $302 · 10th to 90th $151 to $363
$200$500$1Kfacility $631professional $302

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$234.42
Median
$234.42
Typical High
$234.42
Aetna
Setting
Professional
Modifier
None
Typical Low
$234.42
Median
$234.42
Typical High
$239.88
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$117.49
Median
$117.49
Typical High
$120.23
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$46.77
Median
$46.77
Typical High
$47.86
BCBS South Carolina
Setting
Facility
Modifier
None
Typical Low
$1,621.81
Median
$1,621.81
Typical High
$1,659.59
BCBS South Carolina
Setting
Professional
Modifier
None
Typical Low
$302.00
Median
$302.00
Typical High
$323.59
Cigna
Setting
Facility
Modifier
None
Typical Low
$575.44
Median
$758.58
Typical High
$1,862.09
Cigna
Setting
Professional
Modifier
None
Typical Low
$138.04
Median
$165.96
Typical High
$363.08
Medcost
Setting
Facility
Modifier
None
Typical Low
$234.42
Median
$281.84
Typical High
$870.96
Medcost
Setting
Professional
Modifier
None
Typical Low
$302.00
Median
$302.00
Typical High
$426.58
United
Setting
Facility
Modifier
None
Typical Low
$269.15
Median
$269.15
Typical High
$363.08
United
Setting
Professional
Modifier
None
Typical Low
$125.89
Median
$181.97
Typical High
$302.00
1 more rate with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$151.36
Median
$151.36
Typical High
$239.88

Where South Carolina sits

The same service costs 3.9 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 20th of 51

$302

AK $676AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.