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Targeted Gene Sequencing Analysis

Missouri rates for HCPCS 81405

This laboratory analysis examines the DNA sequence of a specific gene associated with an inherited condition, looking for changes that could explain a patient's symptoms or family history. It is one of many single-gene analyzes available, each ordered based on the particular condition being evaluated. Results help confirm a diagnosis or guide further testing and family counseling.

Rates data updated July 2026.

How much does Targeted Gene Sequencing Analysis cost?

$302

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $302 for this service. The price depends on where it is billed: about $263 from a physician practice, and about $389 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$263$182 to $355
FacilityA hospital or hospital-owned outpatient department$389$295 to $525

How much rates vary

Facilitymedian $389 · 10th to 90th $229 to $977Professionalmedian $263 · 10th to 90th $120 to $589
$50$100$200$500$1Kfacility $389professional $263

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$63.10
Median
$478.63
Typical High
$977.24
Aetna
Setting
Professional
Modifier
Global
Typical Low
$257.04
Median
$263.03
Typical High
$616.60
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$302.00
Median
$302.00
Typical High
$1,047.13
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$87.10
Median
$269.15
Typical High
$524.81
BCBS
Setting
Facility
Modifier
Global
Typical Low
$416.87
Median
$446.68
Typical High
$776.25
BCBS
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$302.00
Typical High
$338.84
Cigna
Setting
Facility
Modifier
Global
Typical Low
$229.09
Median
$588.84
Typical High
$912.01
Cigna
Setting
Professional
Modifier
Global
Typical Low
$138.04
Median
$234.42
Typical High
$436.52
Medica
Setting
Facility
Modifier
Global
Typical Low
$263.03
Median
$363.08
Typical High
$1,584.89
Medica
Setting
Professional
Modifier
Global
Typical Low
$125.89
Median
$181.97
Typical High
$1,513.56
United
Setting
Facility
Modifier
Global
Typical Low
$125.89
Median
$302.00
Typical High
$363.08
United
Setting
Professional
Modifier
Global
Typical Low
$125.89
Median
$181.97
Typical High
$407.38

Where Missouri sits

The same service costs 3.9 times more in Alaska than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 25th of 51

$302

AK $676VT $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.