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Targeted Gene Sequencing Analysis

Maryland rates for HCPCS 81405

This laboratory analysis examines the DNA sequence of a specific gene associated with an inherited condition, looking for changes that could explain a patient's symptoms or family history. It is one of many single-gene analyzes available, each ordered based on the particular condition being evaluated. Results help confirm a diagnosis or guide further testing and family counseling.

Rates data updated July 2026.

How much does Targeted Gene Sequencing Analysis cost?

$224

Typical negotiated rate. In Maryland, July 2026.

Insurers have agreed to pay about $224 for this service. Most negotiated rates run $182 to $295.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $1,950 · 10th to 90th $2 to $1,950Professionalmedian $224 · 10th to 90th $135 to $661
$5$20$100$500$2Kfacility $1,950professional $224

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2.24
Median
$1,949.84
Typical High
$1,949.84
Aetna
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$245.47
Typical High
$812.83
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$218.78
Median
$239.88
Typical High
$275.42
Cigna
Setting
Professional
Modifier
Global
Typical Low
$158.49
Median
$199.53
Typical High
$537.03
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$302.00
Median
$363.08
Typical High
$457.09
United
Setting
Facility
Modifier
Global
Typical Low
$125.89
Median
$125.89
Typical High
$1,380.38
United
Setting
Professional
Modifier
Global
Typical Low
$125.89
Median
$134.90
Typical High
$263.03
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$151.36
Median
$151.36
Typical High
$151.36

Where Maryland sits

The same service costs 3.9 times more in Alaska than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 47th of 51

$224

AK $676VT $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.