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Targeted Gene Sequencing Analysis

Kentucky rates for HCPCS 81405

This laboratory analysis examines the DNA sequence of a specific gene associated with an inherited condition, looking for changes that could explain a patient's symptoms or family history. It is one of many single-gene analyzes available, each ordered based on the particular condition being evaluated. Results help confirm a diagnosis or guide further testing and family counseling.

Rates data updated October 2026.

How much does Targeted Gene Sequencing Analysis cost?

$269

Typical negotiated rate. In Kentucky, October 2026.

Insurers have agreed to pay about $269 for this service. The price depends on where it is billed: about $269 from a physician practice, and about $269 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$269$158 to $324
FacilityA hospital or hospital-owned outpatient department$269$245 to $407

How much rates vary

Facilitymedian $269 · 10th to 90th $174 to $1,585Professionalmedian $269 · 10th to 90th $120 to $603
$100$200$500$1Kfacility $269professional $269

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$245.47
Typical High
$251.19
Aetna
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$245.47
Typical High
$302.00
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$186.21
Median
$302.00
Typical High
$316.23
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$120.23
Median
$269.15
Typical High
$331.13
CareSource
Setting
Facility
Modifier
None
Typical Low
$302.00
Median
$407.38
Typical High
$426.58
CareSource
Setting
Professional
Modifier
None
Typical Low
$302.00
Median
$389.05
Typical High
$501.19
Cigna
Setting
Facility
Modifier
None
Typical Low
$234.42
Median
$1,318.26
Typical High
$1,584.89
Cigna
Setting
Professional
Modifier
None
Typical Low
$223.87
Median
$1,445.44
Typical High
$1,445.44
United
Setting
Professional
Modifier
None
Typical Low
$131.83
Median
$181.97
Typical High
$478.63
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$104.71
Median
$123.03
Typical High
$151.36
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$42.66
Median
$48.98
Typical High
$60.26

Where Kentucky sits

The same service costs 3.9 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Kentucky· 32nd of 51

$269

AK $676AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.