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Targeted Gene Sequencing Analysis

Indiana rates for HCPCS 81405

This laboratory analysis examines the DNA sequence of a specific gene associated with an inherited condition, looking for changes that could explain a patient's symptoms or family history. It is one of many single-gene analyzes available, each ordered based on the particular condition being evaluated. Results help confirm a diagnosis or guide further testing and family counseling.

Rates data updated October 2026.

How much does Targeted Gene Sequencing Analysis cost?

$245

Typical negotiated rate. In Indiana, October 2026.

Insurers have agreed to pay about $245 for this service. The price depends on where it is billed: about $186 from a physician practice, and about $302 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$186$120 to $302
FacilityA hospital or hospital-owned outpatient department$302$295 to $603

How much rates vary

Facilitymedian $302 · 10th to 90th $240 to $912Professionalmedian $186 · 10th to 90th $120 to $457
$200$500$1K$2Kfacility $302professional $186

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$245.47
Median
$416.87
Typical High
$1,122.02
Aetna
Setting
Professional
Modifier
None
Typical Low
$223.87
Median
$245.47
Typical High
$457.09
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$239.88
Median
$302.00
Typical High
$912.01
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$120.23
Median
$120.23
Typical High
$457.09
CareSource
Setting
Professional
Modifier
None
Typical Low
$302.00
Median
$331.13
Typical High
$426.58
Cigna
Setting
Facility
Modifier
None
Typical Low
$194.98
Median
$302.00
Typical High
$851.14
Cigna
Setting
Professional
Modifier
None
Typical Low
$158.49
Median
$269.15
Typical High
$575.44
Physicians Health Plan of Northern Indiana
Setting
Facility
Modifier
None
Typical Low
$501.19
Median
$758.58
Typical High
$2,187.76
Physicians Health Plan of Northern Indiana
Setting
Professional
Modifier
None
Typical Low
$218.78
Median
$257.04
Typical High
$457.09
United
Setting
Professional
Modifier
None
Typical Low
$125.89
Median
$181.97
Typical High
$363.08
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$112.20
Median
$123.03
Typical High
$223.87
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$45.71
Median
$48.98
Typical High
$91.20

Where Indiana sits

The same service costs 3.9 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Indiana· 38th of 51

$245

AK $676AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.