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Targeted Gene Sequencing Analysis

Connecticut rates for HCPCS 81405

This laboratory analysis examines the DNA sequence of a specific gene associated with an inherited condition, looking for changes that could explain a patient's symptoms or family history. It is one of many single-gene analyzes available, each ordered based on the particular condition being evaluated. Results help confirm a diagnosis or guide further testing and family counseling.

Rates data updated October 2026.

How much does Targeted Gene Sequencing Analysis cost?

$263

Typical negotiated rate. In Connecticut, October 2026.

Insurers have agreed to pay about $263 for this service. Most negotiated rates run $174 to $437.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $355 · 10th to 90th $191 to $741Professionalmedian $182 · 10th to 90th $138 to $479
$100$200$500$1Kfacility $355professional $182

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$173.78
Typical High
$173.78
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$190.55
Median
$354.81
Typical High
$741.31
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$134.90
Median
$181.97
Typical High
$478.63
Cigna
Setting
Facility
Modifier
None
Typical Low
$251.19
Median
$478.63
Typical High
$1,096.48
Cigna
Setting
Professional
Modifier
None
Typical Low
$169.82
Median
$389.05
Typical High
$676.08
ConnectiCare
Setting
Professional
Modifier
None
Typical Low
$295.12
Median
$398.11
Typical High
$630.96
United
Setting
Professional
Modifier
None
Typical Low
$125.89
Median
$181.97
Typical High
$389.05
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$87.10
Median
$87.10
Typical High
$87.10
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$34.67
Median
$34.67
Typical High
$34.67

Where Connecticut sits

The same service costs 3.9 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Connecticut· 33rd of 51

$263

AK $676AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.