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Targeted Gene Sequencing Analysis

Alabama rates for HCPCS 81405

This laboratory analysis examines the DNA sequence of a specific gene associated with an inherited condition, looking for changes that could explain a patient's symptoms or family history. It is one of many single-gene analyzes available, each ordered based on the particular condition being evaluated. Results help confirm a diagnosis or guide further testing and family counseling.

Rates data updated October 2026.

How much does Targeted Gene Sequencing Analysis cost?

$174

Typical negotiated rate. In Alabama, October 2026.

Insurers have agreed to pay about $174 for this service. The price depends on where it is billed: about $182 from a physician practice, and about $174 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$182$138 to $347
FacilityA hospital or hospital-owned outpatient department$174$174 to $174

How much rates vary

Facilitymedian $174 · 10th to 90th $174 to $257Professionalmedian $182 · 10th to 90th $126 to $347
$200$500$1Kfacility $174professional $182

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$346.74
Median
$346.74
Typical High
$467.74
Aetna
Setting
Professional
Modifier
None
Typical Low
$204.17
Median
$346.74
Typical High
$346.74
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$117.49
Median
$173.78
Typical High
$173.78
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$46.77
Median
$69.18
Typical High
$69.18
BCBS Alabama
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$173.78
Typical High
$173.78
BCBS Alabama
Setting
Professional
Modifier
21 + 22 · Increased work + 24 · Unrelated visit after surgery + 31
Typical Low
$229.09
Median
$338.84
Typical High
$338.84
Cigna
Setting
Facility
Modifier
None
Typical Low
$245.47
Median
$257.04
Typical High
$954.99
Cigna
Setting
Professional
Modifier
None
Typical Low
$131.83
Median
$138.04
Typical High
$229.09
United
Setting
Facility
Modifier
None
Typical Low
$109.65
Median
$269.15
Typical High
$302.00
United
Setting
Professional
Modifier
None
Typical Low
$125.89
Median
$165.96
Typical High
$181.97

Where Alabama sits

The same service costs 3.9 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alabama· 51st of 51

$174

AK $676AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.