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High-Resolution Tissue-Type Test, Single Marker

Connecticut rates for HCPCS 81381

This is a detailed genetic test that examines one specific immune-system marker gene at high resolution, most often used before a bone marrow, stem cell, or organ transplant to see how closely a donor's tissue type matches the recipient's. Fine-grained matching on these markers helps predict how well a transplant will be tolerated. The test is run on a blood sample.

Rates data updated October 2026.

How much does High-Resolution Tissue-Type Test, Single Marker cost?

$117

Typical negotiated rate. In Connecticut, October 2026.

Insurers have agreed to pay about $117 for this service. Most negotiated rates run $87.10 to $204.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $170 · 10th to 90th $54 to $417Professionalmedian $102 · 10th to 90th $76 to $245
$50$100$200$500facility $170professional $102

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$85.11
Median
$85.11
Typical High
$234.42
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$50.12
Median
$162.18
Typical High
$398.11
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$75.86
Median
$102.33
Typical High
$218.78
Cigna
Setting
Facility
Modifier
None
Typical Low
$109.65
Median
$208.93
Typical High
$616.60
Cigna
Setting
Professional
Modifier
None
Typical Low
$85.11
Median
$199.53
Typical High
$380.19
ConnectiCare
Setting
Professional
Modifier
None
Typical Low
$169.82
Median
$223.87
Typical High
$275.42
United
Setting
Professional
Modifier
None
Typical Low
$70.79
Median
$102.33
Typical High
$218.78
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$42.66
Median
$42.66
Typical High
$44.67
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$16.98
Median
$16.98
Typical High
$18.20

Where Connecticut sits

The same service costs 3.5 times more in Alaska than in North Carolina. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Connecticut· 49th of 51

$117

AK $380NC $110

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.