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NPM1 Gene Test For Leukemia

South Dakota rates for HCPCS 81310

This genetic test looks for a change in the NPM1 gene, an alteration that is commonly found in a type of blood cancer called acute myeloid leukemia. Identifying this gene change helps doctors classify the leukemia and can also be used to check for any remaining disease after treatment. Certain NPM1 changes are associated with a better response to treatment than cases without them.

Rates data updated July 2026.

How much does NPM1 Gene Test For Leukemia cost?

$457

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $457 for this service. The price depends on where it is billed: about $372 from a physician practice, and about $468 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$372$191 to $575
FacilityA hospital or hospital-owned outpatient department$468$457 to $468

How much rates vary

Facilitymedian $468 · 10th to 90th $282 to $468Professionalmedian $372 · 10th to 90th $166 to $646
$100$200$500facility $468professional $372

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$281.84
Typical High
$281.84
Aetna
Setting
Professional
Modifier
Global
Typical Low
$165.96
Median
$190.55
Typical High
$229.09
Cigna
Setting
Facility
Modifier
Global
Typical Low
$467.74
Median
$467.74
Typical High
$467.74
Cigna
Setting
Professional
Modifier
Global
Typical Low
$354.81
Median
$467.74
Typical High
$588.84
Medica
Setting
Facility
Modifier
Global
Typical Low
$234.42
Median
$281.84
Typical High
$691.83
Medica
Setting
Professional
Modifier
Global
Typical Low
$125.89
Median
$125.89
Typical High
$1,230.27
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$354.81
Median
$575.44
Typical High
$676.08
United
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$147.91
Typical High
$323.59
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$245.47
Typical High
$245.47

Where South Dakota sits

The same service costs 3.7 times more in Alaska than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 2nd of 51

$457

AK $550VT $148

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.