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Mismatch Repair Gene Test For Inherited Cancer Risk

South Dakota rates for HCPCS 81298

A laboratory test that reads a gene involved in repairing the errors cells make when they copy their DNA, looking for inherited changes that raise the risk of bowel, womb and several related cancers. It is ordered when a personal or family cancer history, or a finding in a tumor sample, points to an inherited cause.

Rates data updated October 2026.

How much does Mismatch Repair Gene Test For Inherited Cancer Risk cost?

$646

Typical negotiated rate. In South Dakota, October 2026.

Insurers have agreed to pay about $646 for this service. The price depends on where it is billed: about $646 from a physician practice, and about $724 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$646$427 to $1,230
FacilityA hospital or hospital-owned outpatient department$724$724 to $1,230

How much rates vary

Facilitymedian $724 · 10th to 90th $447 to $1,230Professionalmedian $646 · 10th to 90th $269 to $1,549
$200$500$1K$2Kfacility $724professional $646

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$446.68
Median
$446.68
Typical High
$724.44
Aetna
Setting
Professional
Modifier
None
Typical Low
$426.58
Median
$426.58
Typical High
$602.56
Cigna
Setting
Facility
Modifier
None
Typical Low
$1,230.27
Median
$1,230.27
Typical High
$1,230.27
Cigna
Setting
Professional
Modifier
None
Typical Low
$741.31
Median
$1,230.27
Typical High
$1,548.82
Medica
Setting
Facility
Modifier
None
Typical Low
$602.56
Median
$724.44
Typical High
$724.44
Medica
Setting
Professional
Modifier
None
Typical Low
$147.91
Median
$436.52
Typical High
$1,174.90
Sanford Health Plan
Setting
Professional
Modifier
None
Typical Low
$575.44
Median
$1,513.56
Typical High
$1,778.28
United
Setting
Professional
Modifier
None
Typical Low
$147.91
Median
$389.05
Typical High
$575.44
Wellmark
Setting
Professional
Modifier
None
Typical Low
$645.65
Median
$645.65
Typical High
$645.65

Where South Dakota sits

The same service costs 5.0 times more in Alaska than in North Carolina. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 21st of 51

$646

AK $1,445NC $288

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.