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Mismatch Repair Gene Test For Inherited Cancer Risk

Nationwide rates for HCPCS 81295

A laboratory test that reads a gene involved in repairing the errors cells make when they copy their DNA, looking for inherited changes that raise the risk of bowel, womb and several related cancers. It is ordered when a personal or family cancer history, or a finding in a tumor sample, points to an inherited cause.

Rates data updated July 2026.

How much does Mismatch Repair Gene Test For Inherited Cancer Risk cost?

$372

Typical negotiated rate. Nationwide, July 2026.

Insurers have agreed to pay about $372 for this service. The price depends on where it is billed: about $309 from a physician practice, and about $537 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 68 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$309$229 to $457
FacilityA hospital or hospital-owned outpatient department$537$380 to $933

How much rates vary

Facilitymedian $537 · 10th to 90th $288 to $1,549Professionalmedian $309 · 10th to 90th $107 to $741
$10$100$1Kfacility $537professional $309

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$288.40
Median
$549.54
Typical High
$1,380.38
Aetna
Setting
Professional
Modifier
Global
Typical Low
$112.20
Median
$316.23
Typical High
$602.56
BCBS
Setting
Facility
Modifier
Global
Typical Low
$316.23
Median
$512.86
Typical High
$1,737.80
BCBS
Setting
Professional
Modifier
Global
Typical Low
$151.36
Median
$229.09
Typical High
$812.83
Cigna
Setting
Facility
Modifier
Global
Typical Low
$162.18
Median
$724.44
Typical High
$1,621.81
Cigna
Setting
Professional
Modifier
Global
Typical Low
$165.96
Median
$446.68
Typical High
$912.01
United
Setting
Facility
Modifier
Global
Typical Low
$138.04
Median
$380.19
Typical High
$457.09
United
Setting
Professional
Modifier
Global
Typical Low
$63.10
Median
$169.82
Typical High
$512.86

What it costs in each state

The same service costs 3.2 times more in Alaska than in North Dakota. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Touch or drag across the chart to see any state's rate.

AK $851ND $269

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.